Abstract
How does an organism produce not only an appropriately sized organ but also the right number of appropriately sized cells in that organ? Examples of correlations between size and number exist, as do instances of independent variation. Autran et al. have characterized the struwwelpeter mutant in Arabidopsis. They find that organ (leaf or petal) size is reduced as a consequence of reduced cell number; in some cases, such as leaf epidermis, there is partial compensation via an enlargement in cell size. It appears that mutation in SWP, which encodes a subunit of the Mediator complex (a transcriptional coactivator), closes the window of cell proliferation earlier, without altering the duration of the cell cycle, meaning that fewer cycles are completed. Partial compensation occurs when the endoreduplication of DNA that accompanies the postmitotic increase in cell size goes on for one or two rounds more than usual. — GJC
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Claims 6
Claim · model-written summary
In the struwwelpeter mutant, leaf or petal size is reduced through reduced cell number.
- Taxon
- Arabidopsis
Arabidopsise0 - Material
- struwwelpeter mutante0
- Organ / stage
- leaf or petale0
- Outcome
- organ (leaf or petal) sizee0
- Direction
- reducede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“struwwelpeter mutant in Arabidopsis. They find that organ (leaf or petal) size is reduced as a consequence of reduced cell number”
Claim · model-written summary
Leaf epidermis partly compensates through increased cell size.
- Taxon
- ArabidopsisArabidopsise1
- Material
- struwwelpeter mutante1
- Organ / stage
- leaf epidermise0
- Outcome
- cell sizee0
- Direction
- enlargemente0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“in some cases, such as leaf epidermis, there is partial compensation via an enlargement in cell size”
e1“struwwelpeter mutant in Arabidopsis”
Claim · model-written summary
SWP mutation appears to shorten the cell proliferation window.
- Taxon
- ArabidopsisArabidopsise1
- Gene
- SWPe0
- Outcome
- window of cell proliferatione0
- Direction
- earliere0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“mutation in SWP, which encodes a subunit of the Mediator complex (a transcriptional coactivator), closes the window of cell proliferation earlier”
e1“struwwelpeter mutant in Arabidopsis”
Claim · model-written summary
SWP mutation does not appear to alter cell cycle duration.
- Taxon
- ArabidopsisArabidopsise2
- Gene
- SWPe1
- Outcome
- duration of the cell cyclee0
- Direction
- without alteringe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“without altering the duration of the cell cycle”
e1“mutation in SWP”
e2“struwwelpeter mutant in Arabidopsis”
Claim · model-written summary
Fewer cell cycles are completed following the earlier closure of the proliferation window.
- Taxon
- ArabidopsisArabidopsise1
- Outcome
- cycles are completede0
- Direction
- fewere0
- Qualifier
- closes the window of cell proliferation earliere2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“meaning that fewer cycles are completed”
e1“struwwelpeter mutant in Arabidopsis”
e2“closes the window of cell proliferation earlier”
Claim · model-written summary
Partial cell size compensation accompanies one or two extra rounds of DNA endoreduplication.
- Taxon
- ArabidopsisArabidopsise1
- Outcome
- Partial compensatione0
- Value
- one or two rounds more than usuale0
- Qualifier
- endoreduplication of DNAe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Partial compensation occurs when the endoreduplication of DNA that accompanies the postmitotic increase in cell size goes on for one or two rounds more than usual.”
e1“struwwelpeter mutant in Arabidopsis”