Paper · 1951 · Annals of Botany

Phytotoxic Effects of some Antibiotics

JOYCE M. WRIGHT

9
claims
16
verbatim quotes
86
citations
1
research areas
—
Not open access

Abstract

The toxicity of a number of antibiotics, coumarin, and 3-indolylacetic acid to wheat, clover, and mustard seedlings has been assessed by a simple germination test. The percentage germination of wheat was not markedly affected by any of the compounds tested although root growth was reduced. Severe inhibition of root growth of the other seeds was usually accompanied by reduction in percentage germination. None of the antibiotics tested were as inhibitory as indolylacetic acid, but most were more toxic than coumarin. The more toxic of the antibiotics were alternaric acid, glutinosin, mycophenolic acid, and gliotoxin. The least toxic were griseofulvin, penicillin, and streptomycin. Higher concentrations of the latter antibiotic were found to have an inhibiting effect on the synthesis of chlorophyll.

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Claims 9

Intervention effectobservedoriginal resultno effectmeasured

Claim · model-written summary

Tested compounds did not markedly affect wheat germination.

Treatment
compounds testede0
Outcome
percentage germinatione0
Direction
not markedly affectede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“The percentage germination of wheat was not markedly affected by any of the compounds tested although root growth was reduced.”

✓ located verbatim in the source · abstract, characters 164–290 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Tested compounds reduced wheat root growth.

Treatment
compounds testede0
Outcome
root growthe0
Direction
reducede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“The percentage germination of wheat was not markedly affected by any of the compounds tested although root growth was reduced.”

✓ located verbatim in the source · abstract, characters 164–290 · show in text ↑
Associationobservedoriginal resultnegativemeasured

Claim · model-written summary

Severe root-growth inhibition in clover was usually accompanied by reduced germination.

Taxon
cloverTrifoliume0
Treatment
Severe inhibition of root growthe1
Outcome
percentage germinatione1
Direction
reductione1
Qualifier
usuallye1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Trifolium
Trifolium · Taxon · picture of the genus (one of its species)AnRo0002 · CC0 · Wikimedia Commons ↗

Verbatim

e0

“wheat, clover, and mustard seedlings”

✓ located verbatim in the source · abstract, characters 79–115 · show in text ↑
e1

“Severe inhibition of root growth of the other seeds was usually accompanied by reduction in percentage germination.”

✓ located verbatim in the source · abstract, characters 291–406 · show in text ↑
Associationobservedoriginal resultnegativemeasured

Claim · model-written summary

Severe root-growth inhibition in mustard was usually accompanied by reduced germination.

Taxon
mustarde0
Treatment
Severe inhibition of root growthe1
Outcome
percentage germinatione1
Direction
reductione1
Qualifier
usuallye1

Verbatim

e0

“wheat, clover, and mustard seedlings”

✓ located verbatim in the source · abstract, characters 79–115 · show in text ↑
e1

“Severe inhibition of root growth of the other seeds was usually accompanied by reduction in percentage germination.”

✓ located verbatim in the source · abstract, characters 291–406 · show in text ↑
Intervention effectobservedoriginal resultmeasured

Claim · model-written summary

Antibiotics were less inhibitory than indolylacetic acid in the seedling tests.

Treatment
antibiotics testede1
Outcome
inhibitorye1
Direction
None of the antibiotics tested were as inhibitorye1
Qualifier
clover, and mustard seedlingse0
Comparator
indolylacetic acide1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“wheat, clover, and mustard seedlings”

✓ located verbatim in the source · abstract, characters 79–115 · show in text ↑
e1

“None of the antibiotics tested were as inhibitory as indolylacetic acid”

✓ located verbatim in the source · abstract, characters 407–478 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Most antibiotics were more toxic than coumarin in the seedling tests.

Treatment
antibiotics testede1
Outcome
toxice1
Direction
more toxice1
Qualifier
moste1
Comparator
coumarine1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“wheat, clover, and mustard seedlings”

✓ located verbatim in the source · abstract, characters 79–115 · show in text ↑
e1

“None of the antibiotics tested were as inhibitory as indolylacetic acid, but most were more toxic than coumarin.”

✓ located verbatim in the source · abstract, characters 407–519 · show in text ↑
Observationobservedoriginal resultnegativemeasured

Claim · model-written summary

Alternaric acid, glutinosin, mycophenolic acid and gliotoxin were the more toxic antibiotics.

Treatment
alternaric acid, glutinosin, mycophenolic acid, and gliotoxine1
Outcome
more toxice1
Direction
more toxice1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“wheat, clover, and mustard seedlings”

✓ located verbatim in the source · abstract, characters 79–115 · show in text ↑
e1

“The more toxic of the antibiotics were alternaric acid, glutinosin, mycophenolic acid, and gliotoxin.”

✓ located verbatim in the source · abstract, characters 520–621 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Griseofulvin, penicillin and streptomycin were the least toxic antibiotics.

Treatment
griseofulvin, penicillin, and streptomycine1
Outcome
least toxice1
Direction
least toxice1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“wheat, clover, and mustard seedlings”

✓ located verbatim in the source · abstract, characters 79–115 · show in text ↑
e1

“The least toxic were griseofulvin, penicillin, and streptomycin.”

✓ located verbatim in the source · abstract, characters 622–686 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Higher streptomycin concentrations inhibited chlorophyll synthesis in the seedling tests.

Treatment
streptomycine1
Outcome
synthesis of chlorophylle1
Direction
inhibiting effecte1
Qualifier
Higher concentrationse1

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“wheat, clover, and mustard seedlings”

✓ located verbatim in the source · abstract, characters 79–115 · show in text ↑
e1

“The least toxic were griseofulvin, penicillin, and streptomycin. Higher concentrations of the latter antibiotic were found to have an inhibiting effect on the synthesis of chlorophyll.”

✓ located verbatim in the source · abstract, characters 622–806 · show in text ↑