Abstract
Abstract Tolpyralate is a new 4-hydroxyphenyl-pyruvate dioxygenase (HPPD)-inhibiting herbicide for POST weed management in corn; however, there is limited information regarding its efficacy. Six field studies were conducted in Ontario, Canada, over 3 yr (2015 to 2017) to determine the biologically effective dose of tolpyralate for the control of eight annual weed species. Tolpyralate was applied POST at six doses from 3.75 to 120 g ai ha −1 and tank mixed at a 1:33.3 ratio with atrazine at six doses from 125 to 4,000 g ha −1 . Regression analysis was performed to determine the effective dose (ED) of tolpyralate, and tolpyralate+atrazine, required to achieve 50%, 80%, or 90% control of eight weed species at 1, 2, 4, and 8 wk after application (WAA). The ED of tolpyralate for 90% control (ED 90 ) of velvetleaf, common lambsquarters, common ragweed, redroot pigweed or Powell amaranth, and green foxtail at 8 WAA was ≤15.5 g ha −1 ; however, tolpyralate alone did not provide 90% control of wild mustard, barnyardgrass, or ladysthumb at 8 WAA at any dose evaluated in this study. In contrast, the ED 90 for all species in this study with tolpyralate+atrazine was ≤13.1+436 g ha −1 , indicating that tolpyralate+atrazine can be highly efficacious at low field doses.
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Claims 5
Claim · model-written summary
Tolpyralate achieved 90% control of velvetleaf, common lambsquarters, common ragweed, redroot pigweed or Powell amaranth, and green foxtail at no more than 15.5 g ha −1 after eight weeks.
- Taxon
- Corn
Zea mays subsp. mayst0
- Treatment
- tolpyralatee0
- Interactor
- velvetleaf
Abutilon theophrastie0weed - Outcome
- 90% controle0
- Value
- ≤15.5 g ha −1e0
- Qualifier
- at 8 WAAe0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“The ED of tolpyralate for 90% control (ED 90 ) of velvetleaf, common lambsquarters, common ragweed, redroot pigweed or Powell amaranth, and green foxtail at 8 WAA was ≤15.5 g ha −1”
t0“Weeds in Corn”
Claim · model-written summary
Tolpyralate alone failed to achieve 90% control of wild mustard at eight weeks.
- Taxon
- Corn
Zea mays subsp. mayst0
- Treatment
- tolpyralate alonee0
- Interactor
- wild mustarde0weed
- Outcome
- control of wild mustarde0
- Direction
- did not providee0
- Qualifier
- at 8 WAAe0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“tolpyralate alone did not provide 90% control of wild mustard, barnyardgrass, or ladysthumb at 8 WAA at any dose evaluated in this study.”
t0“Weeds in Corn”
Claim · model-written summary
Tolpyralate alone failed to achieve 90% control of barnyardgrass at eight weeks.
- Taxon
- Corn
Zea mays subsp. mayst0
- Treatment
- tolpyralate alonee0
- Interactor
- barnyardgrass
Echinochloa crus-gallie0weed - Outcome
- control of wild mustard, barnyardgrass, or ladysthumbe0
- Direction
- did not providee0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“tolpyralate alone did not provide 90% control of wild mustard, barnyardgrass, or ladysthumb at 8 WAA at any dose evaluated in this study.”
t0“Weeds in Corn”
Claim · model-written summary
Tolpyralate alone failed to achieve 90% control of ladysthumb at eight weeks.
- Taxon
- Corn
Zea mays subsp. mayst0
- Treatment
- tolpyralate alonee0
- Interactor
- ladysthumbe0weed
- Outcome
- 90% controle0
- Direction
- did not providee0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“tolpyralate alone did not provide 90% control of wild mustard, barnyardgrass, or ladysthumb at 8 WAA at any dose evaluated in this study.”
t0“Weeds in Corn”
Claim · model-written summary
Tolpyralate plus atrazine reached a 90% control effective dose no higher than 13.1+436 g ha −1 for all tested weeds.
- Taxon
- Corn
Zea mays subsp. mayst0
- Treatment
- tolpyralate+atrazinee0
- Outcome
- ED 90 for all speciese0
- Value
- ≤13.1+436 g ha −1e0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the ED 90 for all species in this study with tolpyralate+atrazine was ≤13.1+436 g ha −1”
t0“Weeds in Corn”
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See all 6 papers →tolpyralate · Echinochloa crus-galli · Zea mays (maize)Results agree
1 paper in the same direction as this paper
- negative
Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.