Abstract
Diabetes mellitus is a metabolic disorder characterized by increased blood glucose levels due to a deficiency of insulin secretion or when insulin resistance occurs. Herbal medicine is one alternative method that can be used to control blood glucose levels and prevent complications of diabetes mellitus. One of the medicinal plants is avocado seeds (Persea americana Mill.) The active compounds contained in avocado seeds that have antidiabetic activity are flavonoids, alkaloids, tannins and saponins. This study aims to determine the content of secondary metabolites in the extract of avocado seed, the effect of extract of avocado seed and the dose of extract of avocado seed that is effective in lowering blood glucose levels. This research was a laboratory experiment using a modified randomized controlled pretest and posttest group design. Test animals used were 30 rats which were divided into six treatment groups, namely normal control, negative control, positive control, a dose of 250, 300 and 350 mg/kg groups. The results showed that extract of avocado seed contained secondary metabolites: flavonoids, alkaloids, saponins, and tanins;extract of avocado seed gave effect to decrease blood glucose levels; extract of avocado seed with a dose of 350 mg/kg was effective in lowering blood glucose levelswith an avarage decrease of 99,8 mg/dL.
Abstract from the paper’s OpenAlex record; open copy licensed cc-by-nc-sa. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 3
Claim · model-written summary
Avocado seed extract contained flavonoids, alkaloids, saponins and tannins.
- Taxon
- Persea americana Mill.
Persea americanae0 - Organ / stage
- seede1
- Outcome
- secondary metabolites: flavonoids, alkaloids, saponins, and taninse1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“avocado seeds (Persea americana Mill.)”
e1“extract of avocado seed contained secondary metabolites: flavonoids, alkaloids, saponins, and tanins”
Claim · model-written summary
Avocado seed extract decreased blood glucose levels.
- Taxon
- Persea americana Mill.Persea americanae0
- Treatment
- extract of avocado seede2
- Outcome
- blood glucose levelse2
- Direction
- decreasee2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“avocado seeds (Persea americana Mill.)”
e2“extract of avocado seed gave effect to decrease blood glucose levels”
Claim · model-written summary
Avocado seed extract at 350 mg/kg lowered blood glucose levels by an average of 99,8 mg/dL.
- Taxon
- Persea americana Mill.Persea americanae0
- Treatment
- extract of avocado seed with a dose of 350 mg/kge3
- Outcome
- blood glucose levelse3
- Direction
- decreasee3
- Value
- 99,8 mg/dLe3
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“avocado seeds (Persea americana Mill.)”
e3“extract of avocado seed with a dose of 350 mg/kg was effective in lowering blood glucose levelswith an avarage decrease of 99,8 mg/dL”
The same questions in other papers
botanical · molecular: metabolites · Persea americana (avocado)Positive and negative results
1 reporting no difference from an alternative
- no effect
Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.