Abstract
Background Silver nanoparticles (AgNPs) have fascinated extensive interest owing to their potential applications, especially in biomedicine.Materials and methods Through this investigation, AgNPs were green synthesized from AgNO3 using Nigella sativa and Piper nigrum aqueous seed extracts as a reducing agent. Biosynthesized AgNPs were characterized using transmission electron microscopy, Fourier-transform infrared spectroscopy, zeta potential, and dynamic light scattering. Antibacterial, antiviral, and anticancer activities of AgNPs were studied. Furthermore, the effect of biosynthesized AgNPs on seed germination and seedling growth of Vicia faba and Zea mays was determined.Results and conclusion Results evoked the ability of N. sativa and P. nigrum aqueous seed extracts to build up AgNPs in spherical shape with average size of 20 and 50 nm, respectively, by using transmission electron microscopy analysis. The results indicate the ability of N. sativa and P. nigrum AgNPs to inhibit both tested gram-positive and gram-negative bacteria. It is conceivable from the results that AgNPs of the N. sativa and P. nigrum are markedly effective against herpes simplex virus-1 in terms of decreased viral load and mortality, exhibiting 83.23 and 94.54% of antiviral activity, respectively. Furthermore, in-vitro studies of N. sativa and P. nigrum AgNPs against hepatocellular carcinoma have shown good cytotoxic effect, with IC50 values equal to 7.12 and 4.98 µg/ml, respectively. AgNPs exert a promoting action on seed germination percentage and seedling growth of both Vicia faba and Zea mays. This study indicated an economical, simple, and efficient ecofriendly technique using aqueous seed extracts of N. sativa and P. nigrum L. for synthesis of AgNPs and confirmed that green AgNPs are safer.
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Claims 9
Claim · model-written summary
Nigella sativa extract produced spherical silver nanoparticles averaging 20 nm.
Verbatim
e0“Results evoked the ability of N. sativa and P. nigrum aqueous seed extracts to build up AgNPs in spherical shape with average size of 20 and 50 nm, respectively”
Claim · model-written summary
Piper nigrum extract produced spherical silver nanoparticles averaging 50 nm.
Verbatim
e0“Results evoked the ability of N. sativa and P. nigrum aqueous seed extracts to build up AgNPs in spherical shape with average size of 20 and 50 nm, respectively”
Claim · model-written summary
Nanoparticles from both extracts inhibited tested gram positive and gram negative bacteria.
- Outcome
- inhibit both tested gram-positive and gram-negative bacteriae0
Not reportedTaxon
Verbatim
e0“The results indicate the ability of N. sativa and P. nigrum AgNPs to inhibit both tested gram-positive and gram-negative bacteria.”
Claim · model-written summary
Nigella sativa nanoparticles showed 83.23% antiviral activity against herpes simplex virus-1.
Not reportedTaxon
Verbatim
e0“AgNPs of the N. sativa and P. nigrum are markedly effective against herpes simplex virus-1 in terms of decreased viral load and mortality, exhibiting 83.23 and 94.54% of antiviral activity, respectively.”
Claim · model-written summary
Piper nigrum nanoparticles showed 94.54% antiviral activity against herpes simplex virus-1.
Not reportedTaxon
Verbatim
e0“AgNPs of the N. sativa and P. nigrum are markedly effective against herpes simplex virus-1 in terms of decreased viral load and mortality, exhibiting 83.23 and 94.54% of antiviral activity, respectively.”
Claim · model-written summary
Nigella sativa nanoparticles had cytotoxicity against hepatocellular carcinoma with IC50 of 7.12 µg/ml.
Not reportedTaxon
Verbatim
e0“N. sativa and P. nigrum AgNPs against hepatocellular carcinoma have shown good cytotoxic effect, with IC50 values equal to 7.12 and 4.98 µg/ml, respectively.”
Claim · model-written summary
Piper nigrum nanoparticles had cytotoxicity against hepatocellular carcinoma with IC50 of 4.98 µg/ml.
Not reportedTaxon
Verbatim
e0“N. sativa and P. nigrum AgNPs against hepatocellular carcinoma have shown good cytotoxic effect, with IC50 values equal to 7.12 and 4.98 µg/ml, respectively.”
Claim · model-written summary
Silver nanoparticles promoted germination and seedling growth in Vicia faba.
- Taxon
- Vicia faba
Vicia fabae0 - Treatment
- AgNPse0
- Outcome
- seed germination percentage and seedling growthe0
- Direction
- promotinge0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“AgNPs exert a promoting action on seed germination percentage and seedling growth of both Vicia faba and Zea mays.”
Claim · model-written summary
Silver nanoparticles promoted germination and seedling growth in Zea mays.
Zea maysNot reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“AgNPs exert a promoting action on seed germination percentage and seedling growth of both Vicia faba and Zea mays.”
The same questions in other papers
silver nanoparticle · growth · Vicia faba (faba bean)Results differ
2 papers in the same direction as this paper · 1 in the opposite direction
- negative
- positive
- positive
silver nanoparticle · growth · Zea mays (maize)Results differ
14 papers in the same direction as this paper
- positive
- positive
- positive
11 papers more in this group
See all 15 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.