Abstract
This study was aimed at analysing the compounds present in the bark extract of Mallotus tetracoccus (Roxb.) Kurz. by GC-MS analysis and also to investigate the cytotoxic and phytotoxic activity of Mallotus tetracoccus (Roxb.) Kurz. bark extract. The major constituents in M. tetracoccus (Roxb.) Kurz. bark extract are thiocyanic acid and 2-propynyl ester (52.04%). It possesses biocidal, antioxidative, antimutagenic and anticancer activity. The cytotoxic activity of bark extract was evaluated by brine shrimp lethality bioassay method and the LC50 value was found to be 84.72 μg/ml compared to taxol 0.85 μg/ml. Phytotoxicity assay showed significant root length inhibition by the extract at the concentrations of 100, 1000 and 10000 ppm. Similarly, seed germination studies shows that the bark extract possess significant inhibition at concentrations of 1000 and 7500 ppm. Key words: Mallotus tetracoccus, GC-MS analysis, thiocyanic acid, furfural, 4H- Pyran-4 -one, 2, 3- Dihydro-3, 5- dihydroxy-6- methyl, cytotoxicity, phytotoxicity, radish seed, artemia salina.
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Claims 3
Claim · model-written summary
Thiocyanic acid and 2-propynyl ester were major bark extract constituents at 52.04%.
- Taxon
- M. tetracoccus (Roxb.) Kurz.
Mallotus tetracoccuse0 - Organ / stage
- barke0
- Outcome
- thiocyanic acid and 2-propynyl estere0
- Value
- 52.04%e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The major constituents in M. tetracoccus (Roxb.) Kurz. bark extract are thiocyanic acid and 2-propynyl ester (52.04%).”
Claim · model-written summary
The bark extract significantly inhibited root length at three tested concentrations.
- Taxon
- radish
Raphanus sativuse1 - Organ / stage
- roote0
- Treatment
- the extract at the concentrations of 100, 1000 and 10000 ppme0
- Outcome
- root lengthe0
- Direction
- inhibitione0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Phytotoxicity assay showed significant root length inhibition by the extract at the concentrations of 100, 1000 and 10000 ppm.”
e1“radish seed”
Claim · model-written summary
The bark extract significantly inhibited seed germination at 1000 and 7500 ppm.
- Taxon
- radishRaphanus sativuse2
- Treatment
- bark extracte0
- Outcome
- seed germinatione1
- Direction
- inhibitione0
- Qualifier
- concentrations of 1000 and 7500 ppme0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the bark extract possess significant inhibition at concentrations of 1000 and 7500 ppm”
e1“seed germination studies”
e2“radish seed”
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