Paper · 2022 · Carpathian Journal of Food Science and Technology

THE INHIBITION POTENTIAL OF THAI-COLORED RICE EXTRACT AGAINST DIABETES RELATED-ENZYMES AND MELANIN BIOSYNTHESIS-RELATED ENZYME

Thitaya Sornkhwan; Saowapa Chumanee; Sompong Sansenya; et al.

7
claims
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verbatim quotes
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citations
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Open access · cc-by-sa

Abstract

Thailand has both colored and non-colored rice. Thai people use rice both for consumption and health treatment. This study investigates the phytochemical profile, -glucosidase and tyrosinase inhibitory activity of water extract, ethanol extract, and methanol extract of 7 cultivars of Thaicolored rice. The results reveal that 7 cultivars of Thai-colored rice had composed of flavonoids, reducing sugar, saponins, and terpenoids. The highest potency against a-glucosidase activity was obtained from rice cultivar 6 of methanol extract with the IC50 value of 1.06 0.13 g.ml -1 , approximately 175-times more efficient than commercial drug acarbose. Moreover, methanol extract of all rice cultivars seems to have higher glucosidase inhibitory activity than other solvent extract and acarbose. In comparison, water extract of all rice cultivars had higher tyrosinase inhibitory activity than other solvents. The highest tyrosinase inhibitory efficiency was also obtained from rice cultivar 6 of water extract with the IC50 values of 10.93 3.41 g.ml -1 . Our results indicated that the highpolarity solvent can extract the bioactive compounds from plants with a high potency of -glucosidase and tyrosinase inhibitory activity. The results also suggested that rice especially colored rice had contained the bio-active compounds which related with -glucosidase and tyrosinase inhibitory activity.

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Claims 7

Observationobservedoriginal resultmeasured

Claim · model-written summary

Seven cultivars of Thai-colored rice contained flavonoids, reducing sugar and saponins.

Outcome
flavonoids, reducing sugar, saponinse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“The results reveal that 7 cultivars of Thai-colored rice had composed of flavonoids, reducing sugar, saponins, and terpenoids”

✓ located verbatim in the source · abstract, characters 303–428 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Seven cultivars of Thai-colored rice contained terpenoids.

Outcome
terpenoidse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“The results reveal that 7 cultivars of Thai-colored rice had composed of flavonoids, reducing sugar, saponins, and terpenoids”

✓ located verbatim in the source · abstract, characters 303–428 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

The methanol extract of rice cultivar 6 had the highest alpha-glucosidase inhibitory potency, approximately 175-times that of acarbose, with an IC50 of 1.06 0.13 g.ml -1.

Material
rice cultivar 6e1
Treatment
methanol extracte1
Outcome
a-glucosidase activitye1
Direction
highest potencye1
Value
1.06 0.13 g.ml -1e1
Qualifier
approximately 175-times more efficient than commercial drug acarbosee1
Comparator
commercial drug acarbosee1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e1

“The highest potency against a-glucosidase activity was obtained from rice cultivar 6 of methanol extract with the IC50 value of 1.06 0.13 g.ml -1 , approximately 175-times more efficient than commercial drug acarbose”

✓ located verbatim in the source · abstract, characters 430–646 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Methanol extracts of all rice cultivars showed higher alpha-glucosidase inhibitory activity than the other solvent extracts and acarbose.

Treatment
methanol extracte2
Outcome
glucosidase inhibitory activitye2
Direction
highere2
Qualifier
seems toe2
Comparator
other solvent extract and acarbosee2

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“The results reveal that 7 cultivars of Thai-colored rice had composed of flavonoids, reducing sugar, saponins, and terpenoids”

✓ located verbatim in the source · abstract, characters 303–428 · show in text ↑
e2

“methanol extract of all rice cultivars seems to have higher glucosidase inhibitory activity than other solvent extract and acarbose”

✓ located verbatim in the source · abstract, characters 658–789 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Water extracts of all rice cultivars had higher tyrosinase inhibitory activity than the other solvents.

Treatment
water extracte3
Outcome
tyrosinase inhibitory activitye3
Direction
highere3
Comparator
other solventse3

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“The results reveal that 7 cultivars of Thai-colored rice had composed of flavonoids, reducing sugar, saponins, and terpenoids”

✓ located verbatim in the source · abstract, characters 303–428 · show in text ↑
e3

“In comparison, water extract of all rice cultivars had higher tyrosinase inhibitory activity than other solvents”

✓ located verbatim in the source · abstract, characters 791–903 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

The water extract of rice cultivar 6 had the highest tyrosinase inhibitory efficiency, with an IC50 of 10.93 3.41 g.ml -1.

Material
rice cultivar 6e4
Treatment
water extracte4
Outcome
tyrosinase inhibitory efficiencye4
Direction
higheste4
Value
10.93 3.41 g.ml -1e4

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e4

“The highest tyrosinase inhibitory efficiency was also obtained from rice cultivar 6 of water extract with the IC50 values of 10.93 3.41 g.ml -1”

✓ located verbatim in the source · abstract, characters 905–1048 · show in text ↑
Associationauthor interpretationoriginal resultmeasured

Claim · model-written summary

Rice, especially colored rice, contains bioactive compounds related to alpha-glucosidase and tyrosinase inhibitory activity.

Compound
bio-active compoundse5
Outcome
-glucosidase and tyrosinase inhibitory activitye5

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e5

“rice especially colored rice had contained the bio-active compounds which related with -glucosidase and tyrosinase inhibitory activity”

✓ located verbatim in the source · abstract, characters 1255–1389 · show in text ↑