Paper · 2024 · Journal of the Korean Society of Food Science and Nutrition

Anti-Inflammatory Activities of Rumohra adiantiformis Extracts in LPS-Stimulated Macrophages

Ji-Won Hur; Dan-Hee Yoo; In-Chul Lee

5
claims
10
verbatim quotes
3
citations
1
research areas
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Open access · cc-by-nc

Abstract

The potential of Rumohra adiantiformis, a type of Polypodiales, as a natural material was studied using a range of physiological activity studies.Rumohra adiantiformis was extracted using hot water or 70% ethanol.Total polyphenol content was higher in the ethanol extract (RUE) than in the hot water extract (RUD).In addition, the electron-donating abilities and ABTS radical scavenging activities of the two extracts were similar to those of the control group, confirming their excellent antioxidant effects.RAW 264.7 cell viability studies showed the two extracts were non-toxic and inhibited nitric oxide by >79% at 500 μg/mL.Furthermore, RUD and RUE concentration-dependently inhibited the protein and mRNA expressions of iNOS and COX-2.Therefore, the study shows that the hot water and 70% ethanol extracts of Rumohra adiantiformis have antioxidant and anti-inflammatory properties and suggests that Rumohra adiantiformis is a potentially useful functional natural material.

Abstract from the paper’s OpenAlex record; open copy licensed cc-by-nc. Read at the source ↗

The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.

Claims 5

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Total polyphenol content was higher in the ethanol extract than in the hot water extract.

Taxon
Rumohra adiantiformisRumohra adiantiformist0
Treatment
ethanol extracte1
Outcome
Total polyphenol contente1
Direction
highere1
Comparator
hot water extracte1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Rumohra adiantiformis
Rumohra adiantiformis · TaxonForest & Kim Starr · CC BY 3.0 · Wikimedia Commons ↗

Verbatim

t0

“Rumohra adiantiformis Extracts”

✓ located verbatim in the source · title, characters 32–62 · show in text ↑
e1

“Total polyphenol content was higher in the ethanol extract (RUE) than in the hot water extract (RUD)”

✓ located verbatim in the source · abstract, characters 213–313 · show in text ↑
Intervention effectobservedoriginal resultno effectmeasured

Claim · model-written summary

Electron-donating and ABTS radical scavenging activities of both extracts were similar to those of the control group.

Taxon
Rumohra adiantiformisRumohra adiantiformist0
Treatment
the two extractse2
Outcome
electron-donating abilities and ABTS radical scavenging activitiese2
Direction
similare2
Comparator
control groupe2

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Rumohra adiantiformis
Rumohra adiantiformis · TaxonForest & Kim Starr · CC BY 3.0 · Wikimedia Commons ↗

Verbatim

t0

“Rumohra adiantiformis Extracts”

✓ located verbatim in the source · title, characters 32–62 · show in text ↑
e2

“the electron-donating abilities and ABTS radical scavenging activities of the two extracts were similar to those of the control group”

✓ located verbatim in the source · abstract, characters 327–460 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

The two extracts were non-toxic to RAW 264.7 cells.

Taxon
Rumohra adiantiformisRumohra adiantiformist0
Outcome
cell viabilitye3

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Rumohra adiantiformis
Rumohra adiantiformis · TaxonForest & Kim Starr · CC BY 3.0 · Wikimedia Commons ↗

Verbatim

t0

“Rumohra adiantiformis Extracts”

✓ located verbatim in the source · title, characters 32–62 · show in text ↑
e3

“RAW 264.7 cell viability studies showed the two extracts were non-toxic”

✓ located verbatim in the source · abstract, characters 509–580 · show in text ↑

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Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Both extracts inhibited nitric oxide by more than 79% at 500 μg/mL.

Taxon
Rumohra adiantiformisRumohra adiantiformist0
Treatment
the two extractse4
Outcome
nitric oxidee4
Direction
inhibitede4
Value
>79%e4
Qualifier
500 μg/mLe4

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Rumohra adiantiformis
Rumohra adiantiformis · TaxonForest & Kim Starr · CC BY 3.0 · Wikimedia Commons ↗

Verbatim

t0

“Rumohra adiantiformis Extracts”

✓ located verbatim in the source · title, characters 32–62 · show in text ↑
e4

“the two extracts were non-toxic and inhibited nitric oxide by >79% at 500 μg/mL”

✓ located verbatim in the source · abstract, characters 549–628 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Both extracts concentration-dependently inhibited protein and mRNA expression of iNOS and COX-2.

Taxon
Rumohra adiantiformisRumohra adiantiformist0
Treatment
RUD and RUEe5
Gene
iNOS and COX-2e5
Outcome
protein and mRNA expressionse5
Direction
inhibitede5
Qualifier
concentration-dependentlye5

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Rumohra adiantiformis
Rumohra adiantiformis · TaxonForest & Kim Starr · CC BY 3.0 · Wikimedia Commons ↗

Verbatim

t0

“Rumohra adiantiformis Extracts”

✓ located verbatim in the source · title, characters 32–62 · show in text ↑
e5

“RUD and RUE concentration-dependently inhibited the protein and mRNA expressions of iNOS and COX-2”

✓ located verbatim in the source · abstract, characters 642–740 · show in text ↑