Abstract
Due to the fast-changing global climate, conventional agricultural systems have to deal with more unpredictable and harsh environmental conditions leading to compromise food production. The application of phytonanotechnology can ensure safer and more sustainable crop production, allowing the target-specific delivery of bioactive molecules with great and partially explored positive effects for agriculture, such as an increase in crop production and plant pathogen reduction. In this study, the effect of free pterostilbene (PTB) and poly(lactic-co-glycolic) acid (PLGA) nanoparticles (NPs) loaded with pterostilbene was investigated on Solanum lycopersicum L. metabolism. An untargeted NMR-based metabolomics approach was used to examine primary and secondary metabolism whereas a targeted HPLC-MS/MS-based approach was used to explore the impact on defense response subjected to anti-oxidant effect of PTB, such as free fatty acids, oxylipins and them impact on hormone biosynthesis, in particular salicylic and jasmonic acid. In tomato leaves after treatment with PTB and PLGA NPs loaded with PTB (NPs + PTB), both NPs + PTB and free PTB treatments increased GABA levels in tomato leaves. In addition, a decrease of quercetin-3-glucoside associated with the increase in caffeic acid was observed suggesting a shift in secondary metabolism towards the biosynthesis of phenylpropanoids and other phenolic compounds. An increase of behenic acid (C22:0) and a remodulation of oxylipin metabolism deriving from the linoleic acid (i.e. 9-HpODE, 13-HpODE and 9-oxo-ODE) and linolenic acid (9-HOTrE and 9-oxoOTrE) after treatment with PLGA NPs and PLGA NPs + PTB were also found as a part of mechanisms of plant redox modulation. To the best of our knowledge, this is the first study showing the role of PLGA nanoparticles loaded with pterostilbene in modulating leaf metabolome and physiology in terms of secondary metabolites, fatty acids, oxylipins and hormones. In perspective, PLGA NPs loaded with PTB could be used to reshape the metabolic profile to allow plant to react more quickly to stresses.
Abstract from the paper’s OpenAlex record; open copy licensed cc-by-nc-nd. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 8
Claim · model-written summary
both NPs + PTB and free PTB treatments increased GABA levels in tomato leaves.
- Taxon
- tomato
Solanum lycopersicume0 - Organ / stage
- leavese0
- Treatment
- NPs + PTBe0
- Outcome
- GABA levelse0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“both NPs + PTB and free PTB treatments increased GABA levels in tomato leaves.”
Claim · model-written summary
both NPs + PTB and free PTB treatments increased GABA levels in tomato leaves.
- Taxon
- tomatoSolanum lycopersicume0
- Organ / stage
- leavese0
- Treatment
- free PTBe0
- Outcome
- GABA levelse0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“both NPs + PTB and free PTB treatments increased GABA levels in tomato leaves.”
Claim · model-written summary
a decrease of quercetin-3-glucoside associated with the increase in caffeic acid was observed
- Taxon
- tomatoSolanum lycopersicume1
- Organ / stage
- leavese1
- Outcome
- quercetin-3-glucosidee0
- Direction
- decreasee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a decrease of quercetin-3-glucoside associated with the increase in caffeic acid was observed”
e1“In tomato leaves after treatment with PTB and PLGA NPs loaded with PTB (NPs + PTB)”
Claim · model-written summary
a decrease of quercetin-3-glucoside associated with the increase in caffeic acid was observed
- Taxon
- tomatoSolanum lycopersicume1
- Organ / stage
- leavese1
- Outcome
- caffeic acide0
- Direction
- increasee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a decrease of quercetin-3-glucoside associated with the increase in caffeic acid was observed”
e1“In tomato leaves after treatment with PTB and PLGA NPs loaded with PTB (NPs + PTB)”
Claim · model-written summary
An increase of behenic acid (C22:0)
- Taxon
- tomatoSolanum lycopersicume1
- Outcome
- behenic acid (C22:0)e0
- Direction
- increasee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“An increase of behenic acid (C22:0)”
e1“In tomato leaves after treatment with PTB and PLGA NPs loaded with PTB (NPs + PTB)”
Claim · model-written summary
a remodulation of oxylipin metabolism deriving from the linoleic acid (i.e. 9-HpODE, 13-HpODE and 9-oxo-ODE) and linolenic acid (9-HOTrE and 9-oxoOTrE) after treatment with PLGA NPs and PLGA NPs + PTB were also found
- Taxon
- tomatoSolanum lycopersicume1
- Treatment
- PLGA NPse0
- Outcome
- remodulation of oxylipin metabolisme0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a remodulation of oxylipin metabolism deriving from the linoleic acid (i.e. 9-HpODE, 13-HpODE and 9-oxo-ODE) and linolenic acid (9-HOTrE and 9-oxoOTrE) after treatment with PLGA NPs and PLGA NPs + PTB were also found”
e1“In tomato leaves after treatment with PTB and PLGA NPs loaded with PTB (NPs + PTB)”
Claim · model-written summary
a remodulation of oxylipin metabolism deriving from the linoleic acid (i.e. 9-HpODE, 13-HpODE and 9-oxo-ODE) and linolenic acid (9-HOTrE and 9-oxoOTrE) after treatment with PLGA NPs and PLGA NPs + PTB were also found
- Taxon
- tomatoSolanum lycopersicume1
- Treatment
- PLGA NPs + PTBe0
- Outcome
- remodulation of oxylipin metabolisme0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a remodulation of oxylipin metabolism deriving from the linoleic acid (i.e. 9-HpODE, 13-HpODE and 9-oxo-ODE) and linolenic acid (9-HOTrE and 9-oxoOTrE) after treatment with PLGA NPs and PLGA NPs + PTB were also found”
e1“In tomato leaves after treatment with PTB and PLGA NPs loaded with PTB (NPs + PTB)”
Claim · model-written summary
PLGA NPs loaded with PTB could be used to reshape the metabolic profile to allow plant to react more quickly to stresses.
- Taxon
- tomatoSolanum lycopersicume1
- Outcome
- reshape the metabolic profilee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“PLGA NPs loaded with PTB could be used to reshape the metabolic profile to allow plant to react more quickly to stresses.”
e1“In tomato leaves after treatment with PTB and PLGA NPs loaded with PTB (NPs + PTB)”
The same questions in other papers
nanoparticle · molecular: metabolites · Solanum lycopersicum (tomato)Positive and negative results
25 papers in the same direction as this paper · 3 in the opposite direction
- negative
- negative
- negative
25 papers more in this group
See all 29 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.