Paper · 2025 · Journal of Natural Remedies

A Systematic Insight into the Pharmacognostical, Phytochemical, Chemo-fingerprinting and Pharmacological Assessment of Citrus maxima

P. Vijayalakshmi; Malarkodi Velraj

10
claims
11
verbatim quotes
0
citations
1
research areas
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Open access

Abstract

Background: Fruits of the citrus family are known for their antioxidant and antimicrobial activity. Aim: The study aims to perform pharmacogenetic and physicochemical analysis of the peel along with the determination of the physical standards, phytochemical analysis, phytochemical identification, antioxidant, and antimicrobial properties of Pomelo peel oil. Methods: Pharmacognostical and physicochemical parameters of the pomelo peel were analysed using the standard procedure recommended by WHO. The essential oil was extracted from the pomelo peel using Clevenger’s apparatus, and physical properties, total phenolic content, total flavonoid content, and chemical analysis with GC-MS were determined for the Citrus maxima oil, utilizing accepted procedures. Using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, the antioxidant activity of the C. maxima oil was also assessed. Antibacterial assay of the Pomelo oil was evaluated against Escherichia coli, Staphylococcus aureus, and Streptococcus agalactiae using the Agar well diffusion technique and by determining the MIC (Minimum Inhibitory Concentration). Results: Pharmacognostical standards for the peel and physical standards for the oil were developed, and limonene was observed as the major constituent in the oil, and Total phenol content was 62.42 ± 4.03 mg of equivalent gallic acid/g of C. maxima oil. The total amount of flavonoids in the pomelo oil is 16.48 ± 0.92. Oil of C. maxima showed potential antioxidant and antimicrobial activity. Conclusion: The study has successfully established pharmacognostical standards and physical properties for Pomelo peel oil, identifying limonene as a major constituent. The oil demonstrated significant antioxidant and antimicrobial activity, highlighting its potential for therapeutic applications. Major Findings: Pomelo peel essential oil was found to contain limonene as the major component and demonstrated significant antioxidant and antimicrobial activity against E. coli, S. aureus, and S. agalactiae. In silico docking supported its potential antibacterial efficacy, highlighting its therapeutic value.

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Claims 10

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Pharmacognostical standards for pomelo peel and physical oil standards were developed.

Taxon
C. maximaCitrus maximae0
Organ / stage
peele0
Outcome
Pharmacognostical standardse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Pharmacognostical standards for the peel and physical standards for the oil were developed, and limonene was observed as the major constituent in the oil, and Total phenol content was 62.42 ± 4.03 mg of equivalent gallic acid/g of C. maxima oil.”

✓ located verbatim in the source · abstract, characters 1144–1389 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Limonene was the major constituent of C. maxima oil.

Taxon
C. maximaCitrus maximae0
Outcome
limonene was observed as the major constituent in the oile0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Pharmacognostical standards for the peel and physical standards for the oil were developed, and limonene was observed as the major constituent in the oil, and Total phenol content was 62.42 ± 4.03 mg of equivalent gallic acid/g of C. maxima oil.”

✓ located verbatim in the source · abstract, characters 1144–1389 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Total phenol content of C. maxima oil was 62.42 ± 4.03 mg of equivalent gallic acid/g.

Taxon
C. maximaCitrus maximae0
Outcome
Total phenol contente0
Value
62.42 ± 4.03 mg of equivalent gallic acid/ge0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Pharmacognostical standards for the peel and physical standards for the oil were developed, and limonene was observed as the major constituent in the oil, and Total phenol content was 62.42 ± 4.03 mg of equivalent gallic acid/g of C. maxima oil.”

✓ located verbatim in the source · abstract, characters 1144–1389 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Total flavonoid amount in pomelo oil was 16.48 ± 0.92.

Taxon
pomeloCitrus maximae0
Outcome
total amount of flavonoidse0
Value
16.48 ± 0.92e0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“The total amount of flavonoids in the pomelo oil is 16.48 ± 0.92.”

✓ located verbatim in the source · abstract, characters 1390–1455 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. maxima oil showed antioxidant activity.

Taxon
C. maximaCitrus maximae0
Outcome
antioxidante0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Oil of C. maxima showed potential antioxidant and antimicrobial activity.”

✓ located verbatim in the source · abstract, characters 1456–1529 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. maxima oil showed antimicrobial activity.

Taxon
C. maximaCitrus maximae0
Outcome
antimicrobial activitye0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Oil of C. maxima showed potential antioxidant and antimicrobial activity.”

✓ located verbatim in the source · abstract, characters 1456–1529 · show in text ↑
Observationobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Pomelo oil had significant antimicrobial activity against E. coli.

Taxon
PomeloCitrus maximae0
Outcome
antimicrobial activity against E. colie0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Major Findings: Pomelo peel essential oil was found to contain limonene as the major component and demonstrated significant antioxidant and antimicrobial activity against E. coli, S. aureus, and S. agalactiae.”

✓ located verbatim in the source · abstract, characters 1829–2038 · show in text ↑
Observationobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Pomelo oil had significant antimicrobial activity against S. aureus.

Taxon
PomeloCitrus maximae0
Outcome
antimicrobial activity against E. coli, S. aureuse0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Major Findings: Pomelo peel essential oil was found to contain limonene as the major component and demonstrated significant antioxidant and antimicrobial activity against E. coli, S. aureus, and S. agalactiae.”

✓ located verbatim in the source · abstract, characters 1829–2038 · show in text ↑
Observationobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Pomelo oil had significant antimicrobial activity against S. agalactiae.

Taxon
PomeloCitrus maximae0
Outcome
antimicrobial activity against E. coli, S. aureus, and S. agalactiaee0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Major Findings: Pomelo peel essential oil was found to contain limonene as the major component and demonstrated significant antioxidant and antimicrobial activity against E. coli, S. aureus, and S. agalactiae.”

✓ located verbatim in the source · abstract, characters 1829–2038 · show in text ↑
Observationobservedoriginal resultpositivesimulated

Claim · model-written summary

In silico docking supported potential antibacterial efficacy of pomelo oil.

Taxon
Citrus maximaCitrus maximat0
Outcome
potential antibacterial efficacye0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Citrus maxima
Citrus maxima · TaxonKurt Stüber [1] · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“In silico docking supported its potential antibacterial efficacy, highlighting its therapeutic value.”

✓ located verbatim in the source · abstract, characters 2039–2140 · show in text ↑
t0

“Citrus maxima”

✓ located verbatim in the source · title, characters 119–132 · show in text ↑