Paper · 2025 · PeerJ

Phenolic compounds profiling of nine dogwood species (Cornus L.) leaves

Vladimír Forman; Kristina Trush; Jana Konôpková; et al.

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21
verbatim quotes
1
citations
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Open access · cc-by

Abstract

This study analysed the phenolic compound profile in the leaves of nine Cornus species ( C. alba , C. amomum , C. sericea var. baileyi , C. florida , C. kousa , C. mas , C. officinalis , C. coreana , and C. racemosa ) to evaluate their potential as stable sources of bioactive compounds. The main phenolic acids (gallic, ellagic and chlorogenic acids) and flavonoids were quantified by high-performance liquid chromatography with diode-array detection (HPLC-DAD). Among the phenolic acids, C. mas and C. officinalis contained the highest levels of chlorogenic acid, while C. coreana totally lacked this compound. Notably, the chlorogenic acid concentration in C. mas also exceeded previously reported values for other plant parts. The highest ellagic acid content was found in C. sericea var. baileyi , while the lowest was observed in C. racemosa . C. coreana showed the highest concentration of gallic acid. Flavonoid analysis revealed that quercetin-3- O -galactoside was present in all species studied, with the highest levels in C. racemosa and the lowest in C. florida . Quercetin-3- O -glucoside was abundant in C. kousa but absent in C. mas . Quercetin-3- O -rhamnoside was detected in significant amounts only in C. racemosa and C. amomum . Among the kaempferol derivatives, kaempferol-3- O -glucoside was the most abundant, with the highest concentration in C. coreana . Furthermore, C. racemosa and C. amomum were the richest sources of quercetin, while C. coreana was particularly rich in kaempferol. These results highlight the diverse phenolic profiles of Cornus species and their potential as valuable sources of bioactive compounds.

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Claims 19

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. mas had among the highest chlorogenic acid levels.

Taxon
C. masCornus mase0
Outcome
chlorogenic acide0
Direction
higheste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus mas
Cornus mas · TaxonB.navez · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“C. mas and C. officinalis contained the highest levels of chlorogenic acid”

✓ located verbatim in the source · abstract, characters 490–564 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. officinalis had among the highest chlorogenic acid levels.

Taxon
C. officinalisCornus officinalise0
Outcome
chlorogenic acide0
Direction
higheste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus officinalis
Cornus officinalis · TaxonTakashi KOIKE · CC0 · iNaturalist ↗

Verbatim

e0

“C. mas and C. officinalis contained the highest levels of chlorogenic acid”

✓ located verbatim in the source · abstract, characters 490–564 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. mas chlorogenic acid exceeded previously reported levels in other plant parts.

Taxon
C. masCornus mase0
Outcome
chlorogenic acid concentratione0
Direction
exceedede0
Comparator
other plant partse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus mas
Cornus mas · TaxonB.navez · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“chlorogenic acid concentration in C. mas also exceeded previously reported values for other plant parts”

✓ located verbatim in the source · abstract, characters 626–729 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. sericea var. baileyi had the highest ellagic acid content.

Taxon
C. sericea var. baileyiCornus sericeae0
Outcome
ellagic acid contente0
Direction
higheste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus sericea
Cornus sericea · TaxonSulfur at en.wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“highest ellagic acid content was found in C. sericea var. baileyi”

✓ located verbatim in the source · abstract, characters 735–800 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

C. racemosa had the lowest ellagic acid content.

Taxon
C. racemosaCornus racemosae0
Outcome
loweste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus racemosa
Cornus racemosa · TaxonMitternacht90 at English Wikipedia · Public domain · Wikimedia Commons ↗

Verbatim

e0

“lowest was observed in C. racemosa”

✓ located verbatim in the source · abstract, characters 813–847 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. coreana had the highest gallic acid concentration.

Taxon
C. coreanae0
Outcome
concentration of gallic acide0
Direction
higheste0

Verbatim

e0

“C. coreana showed the highest concentration of gallic acid”

✓ located verbatim in the source · abstract, characters 850–908 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Quercetin-3- O -galactoside was present in every studied Cornus species.

Taxon
Cornus L.t0
Outcome
quercetin-3- O -galactoside was presente0

Verbatim

e0

“quercetin-3- O -galactoside was present in all species studied”

✓ located verbatim in the source · abstract, characters 943–1005 · show in text ↑
t0

“dogwood species (Cornus L.)”

✓ located verbatim in the source · title, characters 37–64 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. racemosa had the highest quercetin-3- O -galactoside levels.

Taxon
C. racemosaCornus racemosae0
Outcome
highest levelse0
Direction
higheste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus racemosa
Cornus racemosa · TaxonMitternacht90 at English Wikipedia · Public domain · Wikimedia Commons ↗

Verbatim

e0

“highest levels in C. racemosa”

✓ located verbatim in the source · abstract, characters 1016–1045 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

C. florida had the lowest quercetin-3- O -galactoside levels.

Taxon
C. floridaCornus floridae0
Outcome
loweste0
Direction
loweste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus florida
Cornus florida · TaxonNo machine-readable author provided. Koba-chan assumed (based on copyright claims). · CC BY 2.5 · Wikimedia Commons ↗

Verbatim

e0

“lowest in C. florida”

✓ located verbatim in the source · abstract, characters 1054–1074 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Quercetin-3- O -glucoside was abundant in C. kousa.

Taxon
C. kousaCornus kousae0
Outcome
Quercetin-3- O -glucoside was abundante0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus kousa
Cornus kousa · TaxonFamartin · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“Quercetin-3- O -glucoside was abundant in C. kousa”

✓ located verbatim in the source · abstract, characters 1077–1127 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Quercetin-3- O -glucoside was absent in C. mas.

Taxon
C. masCornus mase0
Outcome
absente0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus mas
Cornus mas · TaxonB.navez · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Quercetin-3- O -glucoside was abundant in C. kousa but absent in C. mas”

✓ located verbatim in the source · abstract, characters 1077–1148 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Quercetin-3- O -rhamnoside occurred in significant amounts in C. racemosa.

Taxon
C. racemosaCornus racemosae0
Outcome
Quercetin-3- O -rhamnosidee0
Qualifier
significant amountse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus racemosa
Cornus racemosa · TaxonMitternacht90 at English Wikipedia · Public domain · Wikimedia Commons ↗

Verbatim

e0

“Quercetin-3- O -rhamnoside was detected in significant amounts only in C. racemosa and C. amomum”

✓ located verbatim in the source · abstract, characters 1151–1247 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Quercetin-3- O -rhamnoside occurred in significant amounts in C. amomum.

Taxon
C. amomumCornus amomume0
Outcome
Quercetin-3- O -rhamnosidee0
Qualifier
significant amountse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus amomum
Cornus amomum · TaxonUser:SB_Johnny · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Quercetin-3- O -rhamnoside was detected in significant amounts only in C. racemosa and C. amomum”

✓ located verbatim in the source · abstract, characters 1151–1247 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Kaempferol-3- O -glucoside was the most abundant kaempferol derivative.

Taxon
Cornus L.t0
Outcome
kaempferol-3- O -glucosidee0
Direction
most abundante0

Verbatim

e0

“kaempferol-3- O -glucoside was the most abundant”

✓ located verbatim in the source · abstract, characters 1284–1332 · show in text ↑
t0

“dogwood species (Cornus L.)”

✓ located verbatim in the source · title, characters 37–64 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

C. coreana had the highest kaempferol-3- O -glucoside concentration.

Taxon
C. coreanae0
Outcome
highest concentratione0
Direction
higheste0

Verbatim

e0

“highest concentration in C. coreana”

✓ located verbatim in the source · abstract, characters 1343–1378 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

C. racemosa was among the richest sources of quercetin.

Taxon
C. racemosaCornus racemosae0
Outcome
quercetine0
Direction
richeste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus racemosa
Cornus racemosa · TaxonMitternacht90 at English Wikipedia · Public domain · Wikimedia Commons ↗

Verbatim

e0

“C. racemosa and C. amomum were the richest sources of quercetin”

✓ located verbatim in the source · abstract, characters 1394–1457 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

C. amomum was among the richest sources of quercetin.

Taxon
C. amomumCornus amomume0
Outcome
quercetine0
Direction
richeste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Cornus amomum
Cornus amomum · TaxonUser:SB_Johnny · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“C. racemosa and C. amomum were the richest sources of quercetin”

✓ located verbatim in the source · abstract, characters 1394–1457 · show in text ↑