Search claims · PlantClaims

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

PSK-alpha increased cell density of Taxus canadensis C93AD cultures.

Taxon: Taxus canadensis C93ADTaxus canadensise1
Treatment: PSK-alphae1
Outcome: cell densitye1
Direction: increasee1

Not reportedComparator

Verbatim

e1
“Taxus canadensis C93AD and T. cuspidata PO93X displayed a concentration-dependent response (up to 100 nM PSK-alpha added in first 24 h of culture) with a decrease in initial growth rate, an increase in cell density (dry weight/fresh weight), and increased Taxol production”
✓ located verbatim in the source · abstract, characters 848–1120

Title

Effect of the plant peptide regulator, phytosulfokine‐α, on the growth and Taxol production from Taxus sp. suspension cultures

Beum Jun Kim; Donna M. Gibson; Michael L. Shuler Biotechnology and Bioengineering 2006. doi:10.1002/bit.20934

Other claims from this paper (9)

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

PSK-alpha increased cell density of T. cuspidata PO93X cultures.

Taxon: T. cuspidata PO93XTaxus cuspidatae1
Treatment: PSK-alphae1
Outcome: cell densitye1
Direction: increasee1

Not reportedComparator

Verbatim

e1
“Taxus canadensis C93AD and T. cuspidata PO93X displayed a concentration-dependent response (up to 100 nM PSK-alpha added in first 24 h of culture) with a decrease in initial growth rate, an increase in cell density (dry weight/fresh weight), and increased Taxol production”
✓ located verbatim in the source · abstract, characters 848–1120

Title

Effect of the plant peptide regulator, phytosulfokine‐α, on the growth and Taxol production from Taxus sp. suspension cultures

Beum Jun Kim; Donna M. Gibson; Michael L. Shuler Biotechnology and Bioengineering 2006. doi:10.1002/bit.20934

Other claims from this paper (9)

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

PSK-alpha decreased the initial growth rate of Taxus canadensis C93AD cultures.

Taxon: Taxus canadensis C93ADTaxus canadensise1
Treatment: PSK-alphae1
Outcome: initial growth ratee1
Direction: decreasee1

Not reportedComparator

Verbatim

e1
“Taxus canadensis C93AD and T. cuspidata PO93X displayed a concentration-dependent response (up to 100 nM PSK-alpha added in first 24 h of culture) with a decrease in initial growth rate, an increase in cell density (dry weight/fresh weight), and increased Taxol production”
✓ located verbatim in the source · abstract, characters 848–1120

Title

Effect of the plant peptide regulator, phytosulfokine‐α, on the growth and Taxol production from Taxus sp. suspension cultures

Beum Jun Kim; Donna M. Gibson; Michael L. Shuler Biotechnology and Bioengineering 2006. doi:10.1002/bit.20934

Other claims from this paper (9)

Intervention effect Taxus cuspidata P93AF showed no statistically significant response to PSK-alpha supplementation.
Intervention effect PSK-alpha increased Taxol production in Taxus canadensis C93AD in a concentration-dependent response.
Intervention effect PSK-alpha increased Taxol production in T. cuspidata PO93X in a concentration-dependent response.
Intervention effect PSK-alpha increased cell density of Taxus canadensis C93AD cultures.
Intervention effect PSK-alpha decreased the initial growth rate of T. cuspidata PO93X cultures.
Intervention effect PSK-alpha increased cell density of T. cuspidata PO93X cultures.
Intervention effect Combined PSK-alpha and methyl jasmonate elicitation gave a very strong synergistic response in Taxus canadensis C93AD, with Taxol level approximately 10-fold higher than either treatment alone.
Observation The combined PSK-alpha and MeJA elicitation achieved a Taxol level of 35.3 +/- 2.1 mg/L at day 21 in T. canadensis C93AD.
Observation The combined PSK-alpha and MeJA elicitation achieved 1.83 +/- 0.02 mg Taxol per g dry cell weight at day 21 in T. canadensis C93AD.

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

PSK-alpha decreased the initial growth rate of T. cuspidata PO93X cultures.

Taxon: T. cuspidata PO93XTaxus cuspidatae1
Treatment: PSK-alphae1
Outcome: initial growth ratee1
Direction: decreasee1

Not reportedComparator

Verbatim

e1
“Taxus canadensis C93AD and T. cuspidata PO93X displayed a concentration-dependent response (up to 100 nM PSK-alpha added in first 24 h of culture) with a decrease in initial growth rate, an increase in cell density (dry weight/fresh weight), and increased Taxol production”
✓ located verbatim in the source · abstract, characters 848–1120

Title

Effect of the plant peptide regulator, phytosulfokine‐α, on the growth and Taxol production from Taxus sp. suspension cultures

Beum Jun Kim; Donna M. Gibson; Michael L. Shuler Biotechnology and Bioengineering 2006. doi:10.1002/bit.20934

Other claims from this paper (9)

Intervention effect Taxus cuspidata P93AF showed no statistically significant response to PSK-alpha supplementation.
Intervention effect PSK-alpha increased Taxol production in Taxus canadensis C93AD in a concentration-dependent response.
Intervention effect PSK-alpha increased Taxol production in T. cuspidata PO93X in a concentration-dependent response.
Intervention effect PSK-alpha decreased the initial growth rate of Taxus canadensis C93AD cultures.
Intervention effect PSK-alpha increased cell density of Taxus canadensis C93AD cultures.
Intervention effect PSK-alpha increased cell density of T. cuspidata PO93X cultures.
Intervention effect Combined PSK-alpha and methyl jasmonate elicitation gave a very strong synergistic response in Taxus canadensis C93AD, with Taxol level approximately 10-fold higher than either treatment alone.
Observation The combined PSK-alpha and MeJA elicitation achieved a Taxol level of 35.3 +/- 2.1 mg/L at day 21 in T. canadensis C93AD.
Observation The combined PSK-alpha and MeJA elicitation achieved 1.83 +/- 0.02 mg Taxol per g dry cell weight at day 21 in T. canadensis C93AD.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

PSK-alpha increased Taxol production in Taxus canadensis C93AD in a concentration-dependent response.

Taxon: Taxus canadensis C93ADTaxus canadensise1
Treatment: PSK-alphae1
Outcome: Taxol productione1
Direction: increasede1
Qualifier: concentration-dependent responsee1

Not reportedComparator

Verbatim

e1
“Taxus canadensis C93AD and T. cuspidata PO93X displayed a concentration-dependent response (up to 100 nM PSK-alpha added in first 24 h of culture) with a decrease in initial growth rate, an increase in cell density (dry weight/fresh weight), and increased Taxol production”
✓ located verbatim in the source · abstract, characters 848–1120

Title

Effect of the plant peptide regulator, phytosulfokine‐α, on the growth and Taxol production from Taxus sp. suspension cultures

Beum Jun Kim; Donna M. Gibson; Michael L. Shuler Biotechnology and Bioengineering 2006. doi:10.1002/bit.20934

Other claims from this paper (9)

Intervention effect Taxus cuspidata P93AF showed no statistically significant response to PSK-alpha supplementation.
Intervention effect PSK-alpha increased Taxol production in T. cuspidata PO93X in a concentration-dependent response.
Intervention effect PSK-alpha decreased the initial growth rate of Taxus canadensis C93AD cultures.
Intervention effect PSK-alpha increased cell density of Taxus canadensis C93AD cultures.
Intervention effect PSK-alpha decreased the initial growth rate of T. cuspidata PO93X cultures.
Intervention effect PSK-alpha increased cell density of T. cuspidata PO93X cultures.
Intervention effect Combined PSK-alpha and methyl jasmonate elicitation gave a very strong synergistic response in Taxus canadensis C93AD, with Taxol level approximately 10-fold higher than either treatment alone.
Observation The combined PSK-alpha and MeJA elicitation achieved a Taxol level of 35.3 +/- 2.1 mg/L at day 21 in T. canadensis C93AD.
Observation The combined PSK-alpha and MeJA elicitation achieved 1.83 +/- 0.02 mg Taxol per g dry cell weight at day 21 in T. canadensis C93AD.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

PSK-alpha increased Taxol production in T. cuspidata PO93X in a concentration-dependent response.

Taxon: T. cuspidata PO93XTaxus cuspidatae1
Treatment: PSK-alphae1
Outcome: Taxol productione1
Direction: increasede1
Qualifier: concentration-dependent responsee1

Not reportedComparator

Verbatim

e1
“Taxus canadensis C93AD and T. cuspidata PO93X displayed a concentration-dependent response (up to 100 nM PSK-alpha added in first 24 h of culture) with a decrease in initial growth rate, an increase in cell density (dry weight/fresh weight), and increased Taxol production”
✓ located verbatim in the source · abstract, characters 848–1120

Title

Effect of the plant peptide regulator, phytosulfokine‐α, on the growth and Taxol production from Taxus sp. suspension cultures

Beum Jun Kim; Donna M. Gibson; Michael L. Shuler Biotechnology and Bioengineering 2006. doi:10.1002/bit.20934

Other claims from this paper (9)

Intervention effect Taxus cuspidata P93AF showed no statistically significant response to PSK-alpha supplementation.
Intervention effect PSK-alpha increased Taxol production in Taxus canadensis C93AD in a concentration-dependent response.
Intervention effect PSK-alpha decreased the initial growth rate of Taxus canadensis C93AD cultures.
Intervention effect PSK-alpha increased cell density of Taxus canadensis C93AD cultures.
Intervention effect PSK-alpha decreased the initial growth rate of T. cuspidata PO93X cultures.
Intervention effect PSK-alpha increased cell density of T. cuspidata PO93X cultures.
Intervention effect Combined PSK-alpha and methyl jasmonate elicitation gave a very strong synergistic response in Taxus canadensis C93AD, with Taxol level approximately 10-fold higher than either treatment alone.
Observation The combined PSK-alpha and MeJA elicitation achieved a Taxol level of 35.3 +/- 2.1 mg/L at day 21 in T. canadensis C93AD.
Observation The combined PSK-alpha and MeJA elicitation achieved 1.83 +/- 0.02 mg Taxol per g dry cell weight at day 21 in T. canadensis C93AD.

“decrease in density”

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