Claim · model-written summary
Infection with the mutant virus carrying p19-3M VSR suppressed the recovery phenotype despite free virus siRNAs.
- Taxon
- plantsViridiplantaee2
- Treatment
- mutant virus carrying p19-3M VSRe1
- Interactor
- TombusvirusTombusviruse0pathogen
- Outcome
- recovery phenotypee1
- Qualifier
- despite the presence of free virus specific siRNAse1
Verbatim
e0“a mutant Tombusvirus p19 VSR (p19-3M)”
e1“Infection with the mutant virus carrying p19-3M VSR resulted in suppressed recovery phenotype despite the presence of free virus specific siRNAs”
e2“Analysis of the infected plants revealed that the mutant p19-3M VSR is able to induce miR168 level controlling the accumulation of the antiviral AGO1”
Title
Éva Várallyay; Enikő Oláh; Zoltán Havelda Nucleic Acids Research 2013. doi:10.1093/nar/gkt846
Other claims from this paper (5)
- Observation The mutant p19-3M VSR induces miR168 level, which controls accumulation of the antiviral AGO1 in infected plants.
- Association The miR168-inducing activity is associated with enhanced accumulation of viral RNAs.
- Observation Saturating the siRNA-binding capacity of p19 with defective interfering RNAs did not influence miR168-inducing activity.
- Mechanism p19 VSR has two independent silencing suppressor functions, both required to efficiently cope with the RNA-silencing based host defence.
- Mechanism p19 VSR protein evolved independent parallel capacities to block the host defence at multiple levels.