Claim · model-written summary
The aqueous extract of Zanthoxylum chalybeum inhibited 100% of Ascaris suum worm motility 48 h post exposure, compared with the negative control.
- Taxon
- Zanthoxylum chalybeum
Zanthoxylum chalybeume0 - Treatment
- aqueouse1
- Interactor
- Ascaris suum
Ascaris suume7other - Outcome
- worm motilitye1
- Direction
- inhibitede1
- Value
- 100e1
- Qualifier
- 48 h post exposuree1
- Comparator
- negative controle3
Verbatim
e0“In vitro studies were conducted to determine the anthelmintic activity and phytochemical compounds of Zanthoxylum chalybeum”
e1“The aqueous and ethanolic extracts of the Z. chalybeum inhibited 100 and 93% worm motility, respectively for 48 h post exposure”
e3“There was significant differences in motility inhibition by all dose levels’ that were dose-dependent when compared with negative control”
e7“Ascaris suum model was used for the assays”
Title
S. Nalule African Journal of Pharmacy and Pharmacology 2013. doi:10.5897/ajpp2013.3664
Other claims from this paper (9)
- Intervention effect The ethanolic extract of Zanthoxylum chalybeum inhibited 93% of Ascaris suum worm motility 48 h post exposure, compared with the negative control.
- Observation The ED50 of the ethanolic extract of Zanthoxylum chalybeum was 30.85 mg/ml.
- Observation The ED50 of the aqueous extract of Zanthoxylum chalybeum was 6.28 mg/ml.
- Intervention effect Zanthoxylum chalybeum extracts inhibited motility dose-dependently, with significant differences between dose levels compared with the negative control.
- Intervention effect The potency of Zanthoxylum chalybeum extracts significantly differed from that of albendazole.
- Observation Zanthoxylum chalybeum extracts contained tannins, saponins and flavonoids.
- Observation Zanthoxylum chalybeum extracts contained alkaloids, reducing sugars and coumarin derivatives.
- Observation Zanthoxylum chalybeum extracts contained anthracenones and anthocyanins.
- Observation Thin layer chromatography of Zanthoxylum chalybeum extracts indicated polyphenols and sapogenins.
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