Claim · model-written summary
The authors suggest the leaf-tumor system could assay tumor initiation by chemical and physical agents.
- Taxon
- Graptopetalum paraguayense
_Graptopetalum_paraguayense_-_leaves.jpg?width=60)
Graptopetalum paraguayenset0 - Outcome
- assay for tumor initiation by chemical as well as by physical agentse0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_Graptopetalum_paraguayense_-_leaves.jpg?width=500)
Verbatim
e0“the system described might be useful as an assay for tumor initiation by chemical as well as by physical agents”
t0“Graptopetalum paraguayense”
Title
Leaf tumors induced in Graptopetalum paraguayense by gamma radiation.
O L STEIN; A H SPARROW; L A SCHAIRER PubMed 1959
Other claims from this paper (6)
- Intervention effect High gamma radiation doses induced small protuberances on Graptopetalum leaves after about 5 to 6 weeks.
- Mechanism Histology indicated new tumor-like growth centers causing the protuberances.
- Observation The growth centers were distributed roughly at random and appeared self-limited in size.
- Observation Mature tumors had a dead central region surrounded by rows of small cells.
- Observation A region of cell enlargement commonly surrounded tumors and extended into normal mesophyll.
- Observation The number of tumors per leaf averaged a maximum of about ten in two experiments.