Claim · model-written summary
Lack of MoSET1 up-regulated 1,491 M. oryzae genes in vegetative mycelia.
- Taxon
- wheat host plantse1
- Gene
- MoSET1e0
- Outcome
- M. oryzae genes in the vegetative myceliae0
- Direction
- up-regulatione0
- Value
- 1,491 genese0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingQualifier
Verbatim
e0“Lack of MoSET1 methyltransferase, however, resulted in up-regulation of a significant portion of the M. oryzae genes in the vegetative mycelia (1,491 genes)”
e1“Δmoset1 lost pathogenicity on wheat host plants”
Title
Kieu Thi Minh Pham; Yoshihiro Inoue; Ba Van Vu; et al. PLoS Genetics 2015. doi:10.1371/journal.pgen.1005385
Other claims from this paper (13)
- Observation Eight KMTs contributed to infection processes to varying degrees.
- Intervention effect Moset1 disruption impaired H3K4 methylation and caused the most severe infection morphogenesis defects.
- Intervention effect Δmoset1 lost pathogenicity on wheat.
- Intervention effect Exogenous cAMP greatly restored Δmoset1 appressorium formation.
- Intervention effect Exogenous 16-hydroxypalmitic acid greatly restored Δmoset1 appressorium formation.
- Observation Δmoset1 remained infectious on barley cultivar Nigrate.
- Observation Δmoset1 was impaired in vegetative growth.
- Observation Approximately 5% of M. oryzae genes changed H3K4-me2 or -me3 abundance during infection morphogenesis.
- Association H3K4-me2 and -me3 abundance was positively associated with active transcription.
- Observation Lack of MoSET1 up-regulated 1,385 M. oryzae genes during infection morphogenesis.
- Observation MoSET1 dependence accounted for 1,201 up-regulated genes among mycelium–germination tube DEGs.
- Observation MoSET1 dependence accounted for 882 down-regulated genes among mycelium–germination tube DEGs.
- Observation MoSET1-dependent DEGs were enriched in signal transduction, transport, RNA processing and translation.