Claim · model-written summary
Exogenous cAMP greatly restored Δmoset1 appressorium formation.
- Taxon
- wheat host plantse1
- Treatment
- exogenous addition of cAMPe0
- Outcome
- appressorium formatione0
- Direction
- restorede0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Verbatim
e0“appressorium formation was greatly restored in the Δmoset1 mutants by exogenous addition of cAMP”
e1“Δmoset1 lost pathogenicity on wheat host plants”
Title
Kieu Thi Minh Pham; Yoshihiro Inoue; Ba Van Vu; et al. PLoS Genetics 2015. doi:10.1371/journal.pgen.1005385
Other claims from this paper (13)
- Observation Eight KMTs contributed to infection processes to varying degrees.
- Intervention effect Moset1 disruption impaired H3K4 methylation and caused the most severe infection morphogenesis defects.
- Intervention effect Δmoset1 lost pathogenicity on wheat.
- Intervention effect Exogenous 16-hydroxypalmitic acid greatly restored Δmoset1 appressorium formation.
- Observation Δmoset1 remained infectious on barley cultivar Nigrate.
- Observation Δmoset1 was impaired in vegetative growth.
- Observation Approximately 5% of M. oryzae genes changed H3K4-me2 or -me3 abundance during infection morphogenesis.
- Association H3K4-me2 and -me3 abundance was positively associated with active transcription.
- Observation Lack of MoSET1 up-regulated 1,491 M. oryzae genes in vegetative mycelia.
- Observation Lack of MoSET1 up-regulated 1,385 M. oryzae genes during infection morphogenesis.
- Observation MoSET1 dependence accounted for 1,201 up-regulated genes among mycelium–germination tube DEGs.
- Observation MoSET1 dependence accounted for 882 down-regulated genes among mycelium–germination tube DEGs.
- Observation MoSET1-dependent DEGs were enriched in signal transduction, transport, RNA processing and translation.