Claim · model-written summary
The proposed mechanism has two feedback loops operating at the growing leaf margin.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianat0 - Organ / stage
- growing leaf margine0
- Outcome
- two feedback loops working in concerte0
- Qualifier
- regulatory modulee0
Not reportedMaterialGeneCompoundInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“This mechanism operates at the growing leaf margin via a regulatory module consisting of two feedback loops working in concert.”
t0“Arabidopsis thaliana”
Title
Model for the regulation of Arabidopsis thaliana leaf margin development
Gemma D. Bilsborough; Adam Runions; Michalis Barkoulas; et al. Proceedings of the National Academy of Sciences 2011. doi:10.1073/pnas.1015162108
Other claims from this paper (5)
- Mechanism Serration development is attributed to spatial regulatory peaks of auxin and CUC2 activity.
- Mechanism PIN1 polar membrane localization links auxin transport to its distribution.
- Mechanism CUC2 promotes PIN1-dependent auxin activity maxima.
- Mechanism Auxin represses CUC2 expression.
- Mechanism The CUC2-dependent loop regulates an auxin efflux module to generate stable serration patterns.