Claim · model-written summary
Serration development is attributed to spatial regulatory peaks of auxin and CUC2 activity.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianat0 - Gene
- cup-shaped cotyledon2 (CUC2)e0
- Compound
- auxine0
- Outcome
- serration developmente0
- Qualifier
- spatially distributed regulatory mechanisme0
Not reportedMaterialOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“serration development is the morphological read-out of a spatially distributed regulatory mechanism, which creates interspersed activity peaks of the growth-promoting hormone auxin and the cup-shaped cotyledon2 (CUC2) transcription factor.”
t0“Arabidopsis thaliana”
Title
Model for the regulation of Arabidopsis thaliana leaf margin development
Gemma D. Bilsborough; Adam Runions; Michalis Barkoulas; et al. Proceedings of the National Academy of Sciences 2011. doi:10.1073/pnas.1015162108
Other claims from this paper (5)
- Mechanism The proposed mechanism has two feedback loops operating at the growing leaf margin.
- Mechanism PIN1 polar membrane localization links auxin transport to its distribution.
- Mechanism CUC2 promotes PIN1-dependent auxin activity maxima.
- Mechanism Auxin represses CUC2 expression.
- Mechanism The CUC2-dependent loop regulates an auxin efflux module to generate stable serration patterns.