Intervention effectmodel-written summary

Overexpression of TaTIP41 enhanced drought tolerance in wheat.

A claim from TaTIP41 and TaTAP46 positively regulate drought tolerance in wheat by inhibiting PP2A activity · 2023

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Taxon: wheatTriticum aestivumt0
Treatment: overexpression of TaTIP41e2
Gene: TaTIP41e2
Outcome: drought tolerancee2
Direction: enhancede2

Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

*Triticum aestivum* · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

t0
“positively regulate drought tolerance in wheat”
✓ located verbatim in the source · title, characters 20–66

e2
“The overexpression of TaTIP41 enhanced drought tolerance and the ABA response, including ABA-induced stomatal closure, while its downregulation using RNA interference (RNAi) had the opposite effect”
✓ located verbatim in the source · abstract, characters 451–648

Title

TaTIP41 and TaTAP46 positively regulate drought tolerance in wheat by inhibiting PP2A activity

Jianhui Ma; Yuke Geng; Hong Liu; et al. Journal of Integrative Plant Biology 2023. doi:10.1111/jipb.13542

Other claims from this paper (9)

Observation TaTIP41 homoeologs are expressed in wheat in response to drought stress and abscisic acid.
Intervention effect Overexpression of TaTIP41 enhanced the ABA response in wheat.
Intervention effect Overexpression of TaTIP41 enhanced ABA-induced stomatal closure in wheat.
Intervention effect RNAi downregulation of TaTIP41 decreased drought tolerance and the ABA response in wheat.
Association TaTAP46 positively regulates drought tolerance in wheat.
Observation TaTIP41 physically interacts with TaTAP46 in wheat.
Observation TaTIP41 and TaTAP46 interact with PP2A catalytic subunits such as TaPP2A-2 in wheat.
Association TaTIP41 and TaTAP46 inhibit the enzymatic activity of TaPP2A-2 in wheat.
Intervention effect Silencing TaPP2A-2 improved drought tolerance in wheat.

Record rev-61712c11f8c336fcf46be59abc24b5bf9010677473e39535cf465c98668977d2 · schema claims-v0.9 · position 2 in the model’s answer

Functional evidence on TaTIP41

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

TaTIP41

Triticum aestivum (wheat)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Triticum aestivum (wheat).

Drought tolerance1 paper

Promotes
Overexpression of TaTIP41 enhanced drought tolerance in wheat.
TaTIP41 and TaTAP46 positively regulate drought tolerance in wheat by inhibiting PP2A activity · 2023
gain of function → more of the traitThis claim

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.