Intervention effectmodel-written summary

Silencing TaPP2A-2 improved drought tolerance in wheat.

A claim from TaTIP41 and TaTAP46 positively regulate drought tolerance in wheat by inhibiting PP2A activity · 2023

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Silencing TaPP2A-2 improved drought tolerance in wheat.

Treatment
Silencing TaPP2A-2e6
Gene
TaPP2A-2e6
Outcome
drought tolerancee6
Direction
improvede6

Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

t0

“positively regulate drought tolerance in wheat”

✓ located verbatim in the source · title, characters 20–66
e6

“Silencing TaPP2A-2 improved drought tolerance in wheat”

✓ located verbatim in the source · abstract, characters 979–1033

Title

TaTIP41 and TaTAP46 positively regulate drought tolerance in wheat by inhibiting PP2A activity

Jianhui Ma; Yuke Geng; Hong Liu; et al. Journal of Integrative Plant Biology 2023. doi:10.1111/jipb.13542

Other claims from this paper (9)

Record rev-0bf7cf364f6a47f947dcb790e63cbd4c8c1ead46f640dca08f94b4ff86fbce2f · schema claims-v0.9 · position 10 in the model’s answer

loss of function · tolerance: abiotic · Triticum aestivum (wheat)Positive and negative results

13 papers: 8 positive, 5 negative or no effect

7 papers in the same direction as this claim · 5 in the opposite direction

  1. negative
    TaHsfA2h RNA interference constrained heat tolerance.

    An ABF5b‐HsfA2h/HsfC2a‐NCED2b/POD4/HSP26 module integrates multiple signaling pathway to modulate heat stress tolerance in wheat · 2025

    Opposite direction

  2. negative
    RNA interference of TaBZR2 reduced heat stress tolerance in wheat.

    Somatic embryogenetic receptor kinase TaSERL2 regulates heat stress tolerance in wheat by influencing TaBZR2 protein stability and transcriptional activity · 2025

    Opposite direction

  3. negative
    Cri 4–3 edited wheat had significantly lower cold resistance than Fielder.

    TaTPS11 enhances wheat cold resistance by regulating source-sink factor · 2024 · compared with ‘Fielder’

    Opposite direction

  4. negative
    Silencing TalncR9 reduced wheat drought tolerance.

    Genome-wide analysis of lncRNA in wheat (Triticum aestivum) and functional characterization of TalncR9 in response to drought stress · 2025

    Opposite direction

  5. negative
    Silencing TaCML49-B reduced salt resistance in wheat.

    TaCML49-B, a Calmodulin-like Protein, Interacts with TaIQD23 to Positively Regulate Salt Tolerance in Wheat · 2025

    Opposite direction

  6. positive
    Transient expression and BSMV-mediated gene silencing of TabHLH49 improve drought stress resistance in wheat.

    Transcription factor TabHLH49 positively regulates dehydrin WZY2 gene expression and enhances drought stress tolerance in wheat · 2020

    Same direction

  7. positive
    TaWRKY133 silencing enhanced wheat drought tolerance, growth and antioxidant activity.

    A Group I WRKY Gene, TaWRKY133, Negatively Regulates Drought Resistance in Transgenic Plants · 2022

    Same direction

  8. positive
    Silencing TaMYB4 increased wheat cold tolerance.

    TaWRKY115 enhances cold tolerance by weakening the expression of TaMYB4 on CBFs in common wheat · 2026

    Same direction

4 papers more in this group

See all 13 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.

Functional evidence on TaPP2A-2

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

TaPP2A-2 · Open in the knowledge graph

Triticum aestivum (wheat)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Triticum aestivum (wheat).

Drought tolerance1 paper

  1. Restrains
    Silencing TaPP2A-2 improved drought tolerance in wheat.

    TaTIP41 and TaTAP46 positively regulate drought tolerance in wheat by inhibiting PP2A activity · 2023

    loss of function → more of the traitThis claim

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.