Claim · model-written summary
CBP60b is suggested to directly regulate SARD1 expression.
- Taxon
- Arabidopsis
Arabidopsist0 - Gene
- SARD1e6
- Outcome
- SARD1 expressione6
- Qualifier
- directly regulatese6
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
t0“Arabidopsis CALMODULIN-BINDING PROTEIN 60b”
e6“suggesting that it directly regulates SARD1 expression”
Title
Arabidopsis CALMODULIN-BINDING PROTEIN 60b plays dual roles in plant immunity
Weijie Huang; Zhongshou Wu; Hainan Tian; et al. Plant Communications 2021. doi:10.1016/j.xplc.2021.100213
Other claims from this paper (8)
- Mechanism CBP60b functions as a positive regulator of SNC2-mediated immunity.
- Intervention effect Loss-of-function mutations of CBP60b suppress constitutive SARD1 expression.
- Intervention effect Loss-of-function mutations of CBP60b suppress enhanced disease resistance in cbp60g-1 snc2-1D.
- Intervention effect Overexpression of CBP60b elevates SARD1 expression and constitutive defense responses.
- Intervention effect Transient expression of CBP60b in Nicotiana benthamiana activates the pSARD1::luciferase reporter gene.
- Observation CBP60b is recruited to the promoter region of SARD1.
- Intervention effect Knocking out CBP60b in the wild-type background leads to EDS1-dependent autoimmunity.
- Mechanism CBP60b is suggested to be required for expression of a guardee/decoy or a negative regulator of immunity.