Claim · model-written summary
PbCBM1 competes with AtICS1 for AtPHB3 binding in Arabidopsis.
- Taxon
- Arabidopsis
Arabidopsise2 - Gene
- AtICS1e6
- Outcome
- AtPHB3 bindinge6
- Qualifier
- competes with AtICS1e6
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e2“PbCBM1-overexpressing Arabidopsis showed significantly elevated susceptibility to P. brassicae”
e6“PbCBM1 competes with AtICS1 (Isochorismate synthase 1) for AtPHB3 binding”
Title
Jingyan Fu; Ruijia Zhu; Xinmeng Li; et al. Plant Cell & Environment 2026. doi:10.1111/pce.70638
Other claims from this paper (8)
- Observation The P. brassicae effector PbCBM1 suppresses INF1/BAX-induced cell death.
- Intervention effect Arabidopsis overexpressing PbCBM1 showed significantly elevated susceptibility to P. brassicae.
- Intervention effect The Arabidopsis phb3 mutant showed increased susceptibility to P. brassicae.
- Observation AtPHB3 was identified as an interactor of PbCBM1 in vivo and in vitro in Arabidopsis.
- Intervention effect PbCBM1-overexpressing plants reduced salicylic acid pathway gene expression upon chitin treatment.
- Intervention effect PbCBM1-overexpressing plants reduced isochorismate/SA accumulation upon chitin treatment.
- Mechanism P. brassicae effector PbCBM1 disrupts the AtPHB3-AtICS1 complex and thereby suppresses salicylic acid biosynthesis and immunity in Arabidopsis.
- Recommendation The authors suggest that the PbCBM1-AtPHB3 pathway provides potential targets for breeding clubroot-resistant rapeseed varieties.