Claim · model-written summary
Class X receptors were required for Fusarium head blight disease on wheat.
- Taxon
- wheat
Triticum aestivume0 - Gene
- class X receptorse0
- Outcome
- FHB diseasee0
FusariumNot reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“class X receptors that are required for FHB disease on wheat”
t0“Fusarium head blight”
Title
Non-canonical fungal G-protein coupled receptors promote Fusarium head blight on wheat
Tess Dilks; Kirstie Halsey; Rebecca P. De Vos; et al. PLoS Pathogens 2019. doi:10.1371/journal.ppat.1007666
Other claims from this paper (7)
- Observation Non-classical GPCRs are expanded in Fusarium graminearum.
- Mechanism Absence of a GPCR enhanced the wheat host response and restricted infection progression.
- Mechanism Specific receptor sub-domains were required for virulence.
- Observation The non-classical receptors physically interacted with intracellular G-proteins.
- Intervention effect Disrupting a class X receptor dysregulated transcriptional coordination of virulence traits during infection.
- Mechanism Receptor disruption enhanced wheat defensive responses, including chitinase and cell wall biosynthesis.
- Mechanism Wheat defensive responses produced apoplastic and vascular occlusions that impeded infection.