Claim · model-written summary
The authors suggest that interference with mitochondrial energy metabolism may contribute to the nematicidal effect of compound A1 in M. incognita.
- Taxon
- M. incognita
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Meloidogyne incognitae0 - Outcome
- nematicidal effecte0
- Qualifier
- interference with mitochondrial energy metabolisme0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
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Verbatim
e0“compound A1 significantly inhibited succinate dehydrogenase ( SDH ) activity in M. incognita , suggesting that interference with mitochondrial energy metabolism may contribute to its nematicidal effect”
Title
Zongnan Zhu; Siyu Lu; Xiuhai Gan; et al. Pest Management Science 2026. doi:10.1002/ps.70644
Other claims from this paper (10)
- Intervention effect Compound A1 was toxic to Bursaphelenchus xylophilus with an LC50 of 4.3 mg/L, outperforming the commercial nematicide tioxazafen.
- Intervention effect Compound A1 was toxic to Aphelenchoides besseyi with an LC50 of 1.9 mg/L, outperforming the commercial nematicide tioxazafen.
- Intervention effect Compound A1 was toxic to Meloidogyne incognita with an LC50 of 6.2 mg/L, outperforming the commercial nematicide tioxazafen.
- Intervention effect Compound A1 inhibited nematode egg hatching.
- Intervention effect Compound A1 induced excessive accumulation of reactive oxygen species in nematodes.
- Intervention effect Compound A1 caused vacuolization in nematode tissues.
- Intervention effect In pot experiments, compound A1 reduced nematode invasion of tomato plants.
- Intervention effect In pot experiments, compound A1 enhanced the root defense response of tomato plants.
- Intervention effect Compound A1 significantly inhibited succinate dehydrogenase activity in Meloidogyne incognita.
- Recommendation Thiazole-based compound A1 can serve as a lead compound from which new nematicides can be discovered through structural optimization.