Meloidogyne incognita 326 claims

species · family Meloidogynidae · animal · NCBI Taxonomy ↗

Common name: southern root-knot nematode — NCBI synonyms: Meloidogyne incognita acrita · Oxyuris incognita

5 spellings

Questions studied on this organism9 questions20 papers

Meloidogyne incognitaPhoto by William Wergin and Richard Sayre. Colorized by Stephen Ausmus. U.S. Department of Agriculture · CC BY 2.0 · Wikimedia Commons ↗

326 claims

Open in search (filters, sorting) →

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound A1 was toxic to Meloidogyne incognita with an LC50 of 6.2 mg/L, outperforming the commercial nematicide tioxazafen.

Taxon: Meloidogyne incognitaMeloidogyne incognitae0
Treatment: Compound A1e0
Outcome: median lethal concentration ( LC 50 )e0
Direction: outperforminge0
Value: 6.2e0
Comparator: tioxazafene0

Verbatim

e0
“Compound A1 displayed remarkable toxicity against Bursaphelenchus xylophilus , Aphelenchoides besseyi , and Meloidogyne incognita with median lethal concentration ( LC 50 ) values of 4.3, 1.9, and 6.2 mg/L, respectively, outperforming the commercial nematicide tioxazafen”
✓ located verbatim in the source · abstract, characters 505–776

Title

Design, synthesis, nematicidal activity, and preliminary mechanism of thiazole derivatives through the scaffold hopping strategy

Zongnan Zhu; Siyu Lu; Xiuhai Gan; et al. Pest Management Science 2026. doi:10.1002/ps.70644

Other claims from this paper (10)

Intervention effect Compound A1 was toxic to Bursaphelenchus xylophilus with an LC50 of 4.3 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 was toxic to Aphelenchoides besseyi with an LC50 of 1.9 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 inhibited nematode egg hatching.
Intervention effect Compound A1 induced excessive accumulation of reactive oxygen species in nematodes.
Intervention effect Compound A1 caused vacuolization in nematode tissues.
Intervention effect In pot experiments, compound A1 reduced nematode invasion of tomato plants.
Intervention effect In pot experiments, compound A1 enhanced the root defense response of tomato plants.
Intervention effect Compound A1 significantly inhibited succinate dehydrogenase activity in Meloidogyne incognita.
Mechanism The authors suggest that interference with mitochondrial energy metabolism may contribute to the nematicidal effect of compound A1 in M. incognita.
Recommendation Thiazole-based compound A1 can serve as a lead compound from which new nematicides can be discovered through structural optimization.

Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Compound A1 significantly inhibited succinate dehydrogenase activity in Meloidogyne incognita.

Taxon: M. incognitaMeloidogyne incognitae0
Treatment: compound A1e0
Outcome: succinate dehydrogenase ( SDH ) activitye0
Direction: inhibitede0

Not reportedComparator

Verbatim

e0
“compound A1 significantly inhibited succinate dehydrogenase ( SDH ) activity in M. incognita”
✓ located verbatim in the source · abstract, characters 1135–1227

Title

Design, synthesis, nematicidal activity, and preliminary mechanism of thiazole derivatives through the scaffold hopping strategy

Zongnan Zhu; Siyu Lu; Xiuhai Gan; et al. Pest Management Science 2026. doi:10.1002/ps.70644

Other claims from this paper (10)

Intervention effect Compound A1 was toxic to Bursaphelenchus xylophilus with an LC50 of 4.3 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 was toxic to Aphelenchoides besseyi with an LC50 of 1.9 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 was toxic to Meloidogyne incognita with an LC50 of 6.2 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 inhibited nematode egg hatching.
Intervention effect Compound A1 induced excessive accumulation of reactive oxygen species in nematodes.
Intervention effect Compound A1 caused vacuolization in nematode tissues.
Intervention effect In pot experiments, compound A1 reduced nematode invasion of tomato plants.
Intervention effect In pot experiments, compound A1 enhanced the root defense response of tomato plants.
Mechanism The authors suggest that interference with mitochondrial energy metabolism may contribute to the nematicidal effect of compound A1 in M. incognita.
Recommendation Thiazole-based compound A1 can serve as a lead compound from which new nematicides can be discovered through structural optimization.

Mechanismhypothesisoriginal resultbasis n/a

Claim · model-written summary

The authors suggest that interference with mitochondrial energy metabolism may contribute to the nematicidal effect of compound A1 in M. incognita.

Taxon: M. incognitaMeloidogyne incognitae0
Outcome: nematicidal effecte0
Qualifier: interference with mitochondrial energy metabolisme0

Verbatim

e0
“compound A1 significantly inhibited succinate dehydrogenase ( SDH ) activity in M. incognita , suggesting that interference with mitochondrial energy metabolism may contribute to its nematicidal effect”
✓ located verbatim in the source · abstract, characters 1135–1336

Title

Design, synthesis, nematicidal activity, and preliminary mechanism of thiazole derivatives through the scaffold hopping strategy

Zongnan Zhu; Siyu Lu; Xiuhai Gan; et al. Pest Management Science 2026. doi:10.1002/ps.70644

Other claims from this paper (10)

Intervention effect Compound A1 was toxic to Bursaphelenchus xylophilus with an LC50 of 4.3 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 was toxic to Aphelenchoides besseyi with an LC50 of 1.9 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 was toxic to Meloidogyne incognita with an LC50 of 6.2 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 inhibited nematode egg hatching.
Intervention effect Compound A1 induced excessive accumulation of reactive oxygen species in nematodes.
Intervention effect Compound A1 caused vacuolization in nematode tissues.
Intervention effect In pot experiments, compound A1 reduced nematode invasion of tomato plants.
Intervention effect In pot experiments, compound A1 enhanced the root defense response of tomato plants.
Intervention effect Compound A1 significantly inhibited succinate dehydrogenase activity in Meloidogyne incognita.
Recommendation Thiazole-based compound A1 can serve as a lead compound from which new nematicides can be discovered through structural optimization.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Paroxetine caused 50% mortality in Meloidogyne incognita juveniles at 351.3 µ g/mL.

Taxon: Meloidogyne incognitaMeloidogyne incognitae0
Organ / stage: second‐stage juveniles (J2)e0
Treatment: paroxetinee0
Outcome: mortality (LC 50 )e0
Direction: causede0
Value: 351.3 µ g/mLe0

Not reportedComparator

Verbatim

e0
“paroxetine, which caused 50% mortality (LC 50 ) in second‐stage juveniles (J2) of Meloidogyne incognita at a concentration of 351.3 µ g/mL”
✓ located verbatim in the source · abstract, characters 549–687

Title

Inhibitors of Sodium‐Dependent Serotonin Transporter Protein (SERT) as Potential New Nematicides

Geraldo Jamisse Hodela; Vitor Pereira de Sousa; Mariana Castro de Melo; et al. Chemistry & Biodiversity 2026. doi:10.1002/cbdv.202503443

Other claims from this paper (3)

Method / resource Computational screening selected SERT as the target of chaetoglobosins A and B in Meloidogyne.
Observation Fluensulfone had an LC50 of 39.3 µ g/mL under the same conditions.
Intervention effect Paroxetine reduced pathogenicity of M. incognita juveniles in plant trials.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Fluensulfone had an LC50 of 39.3 µ g/mL under the same conditions.

Taxon: Meloidogyne incognitaMeloidogyne incognitat0
Treatment: fluensulfonee0
Outcome: LC 50e0
Value: 39.3 µ g/mLe0

Verbatim

e0
“the commercial nematicide fluensulfone showed an LC 50 of 39.3 µ g/mL”
✓ located verbatim in the source · abstract, characters 716–785

t0
“Meloidogyne incognita at a concentration”
✓ located verbatim in the source · abstract, characters 631–671

Title

Inhibitors of Sodium‐Dependent Serotonin Transporter Protein (SERT) as Potential New Nematicides

Geraldo Jamisse Hodela; Vitor Pereira de Sousa; Mariana Castro de Melo; et al. Chemistry & Biodiversity 2026. doi:10.1002/cbdv.202503443

Other claims from this paper (3)

Method / resource Computational screening selected SERT as the target of chaetoglobosins A and B in Meloidogyne.
Intervention effect Paroxetine caused 50% mortality in Meloidogyne incognita juveniles at 351.3 µ g/mL.
Intervention effect Paroxetine reduced pathogenicity of M. incognita juveniles in plant trials.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Paroxetine reduced pathogenicity of M. incognita juveniles in plant trials.

Taxon: M. incognitaMeloidogyne incognitae0
Treatment: paroxetinee0
Outcome: pathogenicity of M. incognita J2e0
Direction: reducede0

Not reportedComparator

Verbatim

e0
“In plant trials, paroxetine reduced the pathogenicity of M. incognita J2.”
✓ located verbatim in the source · abstract, characters 787–860

Title

Inhibitors of Sodium‐Dependent Serotonin Transporter Protein (SERT) as Potential New Nematicides

Geraldo Jamisse Hodela; Vitor Pereira de Sousa; Mariana Castro de Melo; et al. Chemistry & Biodiversity 2026. doi:10.1002/cbdv.202503443

Other claims from this paper (3)

Method / resource Computational screening selected SERT as the target of chaetoglobosins A and B in Meloidogyne.
Intervention effect Paroxetine caused 50% mortality in Meloidogyne incognita juveniles at 351.3 µ g/mL.
Observation Fluensulfone had an LC50 of 39.3 µ g/mL under the same conditions.

Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Both compounds suppressed nematode egg hatch to 29.5% from 92.3% in controls.

Taxon: Meloidogyne incognitaMeloidogyne incognitat0
Treatment: ascorbic acid and glutamic acide1
Outcome: egg hatche0
Direction: suppressede0
Value: 29.5%e0
Qualifier: 92.3% in controle0
Comparator: controle0

Verbatim

e0
“Laboratory evaluations proved that both compounds significantly suppressed egg hatch to 29.5% (from 92.3% in control) and elevated juvenile mortality to 62.1% (from 6.0% in control) in a concentration-dependent manner, with ascorbic acid (2 mg/ml) showing the strongest effects.”
✓ located verbatim in the source · abstract, characters 319–597

t0
“Meloidogyne incognita”
✓ located verbatim in the source · title, characters 39–60

e1
“ascorbic acid and glutamic acid”
✓ located verbatim in the source · abstract, characters 195–226

Title

Elicitation of sunflower resistance to Meloidogyne incognita by ascorbic and glutamic acids: integrating direct nematicidal activity and defense enzyme induction

Abdulrahman S. Al-Hussein; Sherif M. El-Ganainy; Wael H. Elmenofy; et al. Journal of the Saudi Society of Agricultural Sciences 2026. doi:10.1007/s44447-026-00162-8

Other claims from this paper (10)

Intervention effect Both compounds elevated juvenile mortality to 62.1% from 6.0% in controls.
Intervention effect Ascorbic acid at 2 mg/ml showed the strongest nematicidal effects, which were concentration dependent.
Intervention effect Foliar acid applications suppressed sunflower nematode root galling by up to 59%.
Intervention effect Foliar acid applications suppressed nematode population density by up to 57%.
Intervention effect Acid applications boosted sunflower shoot fresh weight by 21.1%.
Intervention effect Acid applications boosted sunflower root fresh weight by 24.8%.
Intervention effect Treated sunflower plants had increased peroxidase, phenylalanine ammonia-lyase and superoxide dismutase activities.
Intervention effect Treated sunflower plants had increased ascorbate peroxidase activity.
Intervention effect Pre-inoculation treatments were more efficient, interpreted as priming defense activation.
Mechanism The authors interpret combined direct nematicidal activity and host defense induction as promising for sunflower nematode management.

Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Both compounds elevated juvenile mortality to 62.1% from 6.0% in controls.

Taxon: Meloidogyne incognitaMeloidogyne incognitat0
Treatment: ascorbic acid and glutamic acide1
Outcome: juvenile mortalitye0
Direction: elevatede0
Value: 62.1%e0
Qualifier: 6.0% in controle0
Comparator: controle0

Verbatim

e0
“Laboratory evaluations proved that both compounds significantly suppressed egg hatch to 29.5% (from 92.3% in control) and elevated juvenile mortality to 62.1% (from 6.0% in control) in a concentration-dependent manner, with ascorbic acid (2 mg/ml) showing the strongest effects.”
✓ located verbatim in the source · abstract, characters 319–597

t0
“Meloidogyne incognita”
✓ located verbatim in the source · title, characters 39–60

e1
“ascorbic acid and glutamic acid”
✓ located verbatim in the source · abstract, characters 195–226

Title

Elicitation of sunflower resistance to Meloidogyne incognita by ascorbic and glutamic acids: integrating direct nematicidal activity and defense enzyme induction

Abdulrahman S. Al-Hussein; Sherif M. El-Ganainy; Wael H. Elmenofy; et al. Journal of the Saudi Society of Agricultural Sciences 2026. doi:10.1007/s44447-026-00162-8

Other claims from this paper (10)

Intervention effect Both compounds suppressed nematode egg hatch to 29.5% from 92.3% in controls.
Intervention effect Ascorbic acid at 2 mg/ml showed the strongest nematicidal effects, which were concentration dependent.
Intervention effect Foliar acid applications suppressed sunflower nematode root galling by up to 59%.
Intervention effect Foliar acid applications suppressed nematode population density by up to 57%.
Intervention effect Acid applications boosted sunflower shoot fresh weight by 21.1%.
Intervention effect Acid applications boosted sunflower root fresh weight by 24.8%.
Intervention effect Treated sunflower plants had increased peroxidase, phenylalanine ammonia-lyase and superoxide dismutase activities.
Intervention effect Treated sunflower plants had increased ascorbate peroxidase activity.
Intervention effect Pre-inoculation treatments were more efficient, interpreted as priming defense activation.
Mechanism The authors interpret combined direct nematicidal activity and host defense induction as promising for sunflower nematode management.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Ascorbic acid at 2 mg/ml showed the strongest nematicidal effects, which were concentration dependent.

Taxon: Meloidogyne incognitaMeloidogyne incognitat0
Treatment: ascorbic acid (2 mg/ml)e0
Outcome: strongest effectse0
Direction: strongeste0
Qualifier: concentration-dependente0

Not reportedComparator

Verbatim

e0
“in a concentration-dependent manner, with ascorbic acid (2 mg/ml) showing the strongest effects”
✓ located verbatim in the source · abstract, characters 501–596

t0
“Meloidogyne incognita”
✓ located verbatim in the source · title, characters 39–60

Title

Elicitation of sunflower resistance to Meloidogyne incognita by ascorbic and glutamic acids: integrating direct nematicidal activity and defense enzyme induction

Abdulrahman S. Al-Hussein; Sherif M. El-Ganainy; Wael H. Elmenofy; et al. Journal of the Saudi Society of Agricultural Sciences 2026. doi:10.1007/s44447-026-00162-8

Other claims from this paper (10)

Intervention effect Both compounds suppressed nematode egg hatch to 29.5% from 92.3% in controls.
Intervention effect Both compounds elevated juvenile mortality to 62.1% from 6.0% in controls.
Intervention effect Foliar acid applications suppressed sunflower nematode root galling by up to 59%.
Intervention effect Foliar acid applications suppressed nematode population density by up to 57%.
Intervention effect Acid applications boosted sunflower shoot fresh weight by 21.1%.
Intervention effect Acid applications boosted sunflower root fresh weight by 24.8%.
Intervention effect Treated sunflower plants had increased peroxidase, phenylalanine ammonia-lyase and superoxide dismutase activities.
Intervention effect Treated sunflower plants had increased ascorbate peroxidase activity.
Intervention effect Pre-inoculation treatments were more efficient, interpreted as priming defense activation.
Mechanism The authors interpret combined direct nematicidal activity and host defense induction as promising for sunflower nematode management.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Foliar acid applications suppressed nematode population density by up to 57%.

Taxon: Meloidogyne incognitaMeloidogyne incognitat0
Treatment: pre- and post-inoculation foliar application of these acidse0
Outcome: population densitye0
Direction: suppressede0
Value: up to 57%e0
Comparator: inoculated controlse0

Verbatim

e0
“pre- and post-inoculation foliar application of these acids suppressed nematode root galling by up to 59% and population density by up to 57%, while boosting shoot fresh weight by 21.1% and root fresh weight by 24.8% compared to inoculated controls”
✓ located verbatim in the source · abstract, characters 636–884

t0
“Meloidogyne incognita”
✓ located verbatim in the source · title, characters 39–60

Title

Elicitation of sunflower resistance to Meloidogyne incognita by ascorbic and glutamic acids: integrating direct nematicidal activity and defense enzyme induction

Abdulrahman S. Al-Hussein; Sherif M. El-Ganainy; Wael H. Elmenofy; et al. Journal of the Saudi Society of Agricultural Sciences 2026. doi:10.1007/s44447-026-00162-8

Other claims from this paper (10)

Intervention effect Both compounds suppressed nematode egg hatch to 29.5% from 92.3% in controls.
Intervention effect Both compounds elevated juvenile mortality to 62.1% from 6.0% in controls.
Intervention effect Ascorbic acid at 2 mg/ml showed the strongest nematicidal effects, which were concentration dependent.
Intervention effect Foliar acid applications suppressed sunflower nematode root galling by up to 59%.
Intervention effect Acid applications boosted sunflower shoot fresh weight by 21.1%.
Intervention effect Acid applications boosted sunflower root fresh weight by 24.8%.
Intervention effect Treated sunflower plants had increased peroxidase, phenylalanine ammonia-lyase and superoxide dismutase activities.
Intervention effect Treated sunflower plants had increased ascorbate peroxidase activity.
Intervention effect Pre-inoculation treatments were more efficient, interpreted as priming defense activation.
Mechanism The authors interpret combined direct nematicidal activity and host defense induction as promising for sunflower nematode management.