Claim · model-written summary
Authors conclude aluminum binds a verapamil-specific channel site distinct from the bepridil-specific site.
- Taxon
- Amaranthus tricolor
Amaranthus tricolore1 - Outcome
- net (45)Ca(2+) uptakee0
- Qualifier
- binding to the verapamil-specific channel sitee0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_01.jpg?width=500)
Verbatim
e0“Al ions affect net (45)Ca(2+) uptake by binding to the verapamil-specific channel site that is different from the bepridil-specific one”
e1“Amaranthus tricolor protoplasts”
Title
Mechanism of Aluminum Inhibition of Net 45Ca2+ Uptake by Amaranthus Protoplasts
Zdenko Rengel; Daphne C. Elliott PLANT PHYSIOLOGY 1992. doi:10.1104/pp.98.2.632
Other claims from this paper (14)
- Observation Calcium uptake increased for 3 to 6 minutes then leveled off or declined.
- Intervention effect Aluminum decreased net calcium uptake.
- Intervention effect Verapamil decreased net calcium uptake.
- Intervention effect Bepridil decreased net calcium uptake.
- Intervention effect Aluminum plus bepridil caused a more pronounced calcium uptake decrease.
- Intervention effect Aluminum did not aggravate verapamil-associated calcium uptake reduction.
- Intervention effect Erythrosin B increased calcium uptake.
- Intervention effect Calmidazolium increased calcium uptake.
- Intervention effect Their uptake-increasing effect was undetectable with aluminum.
- Intervention effect Mycophenolic acid decreased calcium uptake.
- Intervention effect Guanosine alleviated the mycophenolic acid effect.
- Intervention effect Mycophenolic acid did not aggravate aluminum-associated uptake reduction.
- Intervention effect Calcium uptake was generally lower at pH 4.5 than pH 5.5.
- Mechanism Authors conclude aluminum interferes with guanosine triphosphate-binding proteins.