Claim · model-written summary
New protein synthesis is blocked specifically in cold-exposed los1-1 plants.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae1 - Material
- los1-1e0
- Treatment
- colde0
- Outcome
- new protein synthesise0
- Direction
- blockede0
Not reportedGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“new protein synthesis is blocked in los1-1 mutant plants specifically in the cold”
e1“Arabidopsis thaliana mutants”
Title
Yan Guo; Liming Xiong; Manabu Ishitani; et al. Proceedings of the National Academy of Sciences 2002. doi:10.1073/pnas.112040099
Other claims from this paper (8)
- Intervention effect The los1-1 mutation blocks cold-induced transcription of cold-responsive genes.
- Intervention effect The los1-1 mutation enhances cold-induced CBF/DREB1 expression.
- Intervention effect The los1-1 mutation reduces capacity to develop freezing tolerance.
- Intervention effect The los1-1 mutation did not impair the vernalization response.
- Observation Genetic analysis found los1-1 is recessive in a single nuclear gene.
- Observation LOS1 encodes a translation elongation factor 2-like protein.
- Mechanism The authors infer new protein synthesis is critical for cold signal transduction.
- Mechanism The authors suggest CBF/DREB1 transcription is feedback inhibited by its products or downstream target products.