Claim · model-written summary
Overexpression and editing showed TaWRKY115 positively modulates wheat cold tolerance.
- Taxon
- wheat
Triticum aestivume0 - Treatment
- Overexpression and CRISPR/Cas9-mediated gene-editinge0
- Gene
- TaWRKY115e0
- Outcome
- cold tolerancee0
- Direction
- positivelye0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“Overexpression and CRISPR/Cas9-mediated gene-editing revealed TaWRKY115 positively modulating cold tolerance in wheat”
Title
TaWRKY115 enhances cold tolerance by weakening the expression of TaMYB4 on CBFs in common wheat
Jinyuan Liu; Yaoyao Jiang; Lei Zhao; et al. National Science Review 2026. doi:10.1093/nsr/nwag087
Other claims from this paper (10)
- Observation Integrated association and RNA-seq analysis identified TaWRKY115 as affecting wheat cold tolerance.
- Mechanism TaSP1 negatively regulates wheat cold tolerance by binding the TaWRKY115 promoter in cold-sensitive haplotypes.
- Mechanism TaWRKY115 inhibited TaMYB4 at protein level.
- Mechanism TaWRKY115 inhibited TaMYB4 at transcription level.
- Intervention effect Silencing TaMYB4 increased wheat cold tolerance.
- Observation TaMYB4 EMS mutants had increased wheat cold tolerance.
- Mechanism TaMYB4 repressed TaCBF family expression by binding their promoters.
- Intervention effect Silencing TaCBF12d decreased wheat cold tolerance.
- Observation TaCBF12d EMS mutants had decreased wheat cold tolerance.
- Mechanism The authors propose a TaSP1-TaWRKY115-TaMYB4 regulatory model acting through TaCBF in wheat cold tolerance.