Claim · model-written summary
Chalcone 2 (butein) was the most active isolated flavonoid, with a MIC of 12.5 microg/ml.
- Taxon
- Butea monosperma
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Butea monospermae0 - Compound
- chalcone 2e4
- Outcome
- antimycobacterial activitye4
- Direction
- most activee4
- Value
- MIC 12.5 microg/mle4
Not reportedMaterialGeneOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
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Verbatim
e0“isolated from the flowers of Butea monosperma”
e4“The isolated flavonoids exhibited varying antimycobacterial activity with the chalcone 2 being the most active compound (MIC 12.5 microg/ml)”
Title
Bioactive Flavonoids of the Flowers of Butea monosperma
Ratchanaporn Chokchaisiri; Channarong Suaisom; Siriluk Sriphota; et al. Chemical and Pharmaceutical Bulletin 2009. doi:10.1248/cpb.57.428
Other claims from this paper (11)
- Observation A new dihydrochalcone, dihydromonospermoside (7), was isolated from the flowers of Butea monosperma.
- Observation Three known chalcones, butein (2), monospermoside (4) and isoliquiritigenin (8), were isolated from the flowers of Butea monosperma.
- Observation Flavanones (-)-butin (1a), (-)-butrin (3a) and (+)-isomonospermoside (5b) were isolated from the flowers of Butea monosperma.
- Observation The flavone 7,3',4'-trihydroxyflavone (6) was isolated from the flowers of Butea monosperma.
- Observation The flavanone (-)-liquiritigenin (9a) was isolated from the flowers of Butea monosperma.
- Observation Three isoflavones, formononetin (10), afrormosin (11) and formononetin-7-O-beta-D-glucopyranoside (12), were isolated from the flowers of Butea monosperma.
- Observation The absolute configuration at the 2-position of flavanone 1a is 2S.
- Observation The absolute configuration at the 2-position of flavanone 3a is 2S.
- Observation The absolute configuration at the 2-position of flavanone 5b is 2R.
- Observation The absolute configuration at the 2-position of flavanone 9a is 2S.
- Observation The isolated flavonoids showed varying antimycobacterial activity.