Claim · model-written summary
Nitrate treatment restrained viral genomic RNA accumulation.
- Taxon
- Malus domestica
Malus domesticat0 - Treatment
- nitrate treatmente0
- Interactor
- ApNMVe0pathogen
- Gene
- MdBT2e0
- Outcome
- ApNMV genomic RNA accumulatione0
- Direction
- restrainse0
Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“nitrate treatment restrains ApNMV genomic RNA accumulation by destabilizing viral replication protein 1a through the MdBT2‐mediated ubiquitin‐proteasome pathway.”
t0“Malus domestica”
Title
Zhenlu Zhang; Yin‐Huan Xie; Ping Sun; et al. Molecular Plant Pathology 2021. doi:10.1111/mpp.13166
Other claims from this paper (6)
- Observation MdBT2 interacted with viral protein 1a in vivo and in vitro.
- Method / resource MdBT2 was identified in a yeast two-hybrid screen using 1a.
- Mechanism MdBT2 promoted viral 1a ubiquitination and degradation independently of MdCUL3A.
- Intervention effect MdBT2 overexpression reduced viral RNA accumulation versus wild type.
- Intervention effect MdBT2 antisense enhanced viral RNA accumulation versus wild type.
- Mechanism MdBT2 interfered with the interaction of viral 1a and 2a pol.