Claim · model-written summary
The sic-4 mutant exhibited PCD.
- Taxon
- Arabidopsis (Arabidopsis thaliana)
Arabidopsis thalianae0 - Material
- sic-4e0
- Outcome
- exhibited PCDe0
Not reportedGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“In Arabidopsis (Arabidopsis thaliana), the loss-of-function mutant of SIC, sic-4, hyperaccumulated lariat intronic RNAs (lariRNAs) and exhibited PCD”
Title
Chengyun Wu; Weibo Zhen; Xingsong Wang; et al. PLANT PHYSIOLOGY 2023. doi:10.1093/plphys/kiad192
Other claims from this paper (9)
- Mechanism SIC represses programmed cell death.
- Observation The sic-4 mutant accumulated lariat intronic RNAs.
- Intervention effect DBR1 overexpression reduced lariRNAs in sic-4.
- Intervention effect DBR1 overexpression suppressed PCD in sic-4.
- Observation The dbr1-2 mutant exhibited PCD.
- Observation The sic-4 mutation disturbed splicing and decay of mRNAs associated with SA homeostasis.
- Observation SA increased dramatically in sic-4.
- Intervention effect Disrupting SA biosynthesis and signaling suppressed PCD in sic-4.
- Mechanism SIC regulates SA-triggered PCD.