Claim · model-written summary
CPL1 inhibits MPK3 activity in a feedback loop.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae1 - Gene
- CPL1e0
- Outcome
- MPK3 activitye0
- Direction
- inhibitse0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“CPL1 inhibits MPK3 activity, creating a feedback loop that regulates HYL1 phosphorylation”
e1“Arabidopsis (Arabidopsis thaliana)”
Title
Yiming Cao; Jiaxin Zhang; Zhong Zhao; et al. The Plant Cell 2025. doi:10.1093/plcell/koaf092
Other claims from this paper (6)
- Mechanism Heat stress induces most miRNAs primarily through enhanced nuclear HYL1 localization.
- Intervention effect Disrupting miRNA biogenesis increased heat stress susceptibility.
- Mechanism HYL1 phosphorylation modulates nuclear localization during heat stress.
- Mechanism MPK3 phosphorylates and stabilizes CPL1.
- Intervention effect MPK3 disruption increased nuclear HYL1 and miRNA production.
- Observation MPK3 mutants had enhanced heat stress tolerance.