Claim · model-written summary
The FgIsw1 deletion strain was unable to produce DON.
- Taxon
- Fusarium graminearum
_on_Corn_(Zea_mays)_at_Waimea%2C_Hawaii.jpg?width=60)
Fusarium graminearume1 - Treatment
- ΔFgIsw1e0
- Outcome
- produce DONe0
- Direction
- unablee0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_on_Corn_(Zea_mays)_at_Waimea%2C_Hawaii.jpg?width=500)
Verbatim
e0“ΔFgIsw1 was unable to produce DON and lost its virulence on the host plant.”
e1“the phytopathogenic fungus Fusarium graminearum”
Title
Fungal chromatin remodeler Isw1 modulates translation via regulating tRNA transcription
Jing Wang; Yueqi Zhang; Jingrui Wang; et al. Nucleic Acids Research 2025. doi:10.1093/nar/gkaf225
Other claims from this paper (7)
- Observation Putrescine globally changed fungal chromatin accessibility.
- Observation FgIsw1 emerged as a key chromatin accessibility regulator.
- Intervention effect FgIsw1 deletion did not affect DON biosynthesis gene transcription.
- Intervention effect FgIsw1 deletion significantly disrupted tRNA transcription.
- Intervention effect FgIsw1 deletion caused a dramatic decline in translation of DON biosynthesis enzymes.
- Mechanism FgIsw1 maintains nucleosome phasing in tRNA chromatin regions for efficient tRNA transcription.
- Intervention effect The FgIsw1 deletion strain lost virulence on the host plant.