By organism › Fungi › Nectriaceae › Fusarium graminearum

Observationauthor interpretationoriginal resultpositivemeasured

Claim · model-written summary

Fusarium secondary metabolite gene clusters contribute broadly to growth, asexual development and abiotic stress adaptation.

Taxon: Fusarium graminearumFusarium graminearumt0
Gene: SM-BGCse0
Outcome: vegetative growth, asexual development, and abiotic stress adaptatione0

Verbatim

e0
“SM-BGCs are broadly integrated into vegetative growth, asexual development, and abiotic stress adaptation”
✓ located verbatim in the source · abstract, characters 683–788

t0
“Fusarium graminearum”
✓ located verbatim in the source · title, characters 128–148

Title

A functional atlas of secondary metabolite biosynthetic gene clusters governing growth, stress adaptation, and pathogenicity in Fusarium graminearum

Hao Qi; Liwen Zhao; Luona Xu; et al. Crop Health 2026. doi:10.1007/s44297-026-00070-x

Other claims from this paper (5)

Observationobservedoriginal resultmeasured

Claim · model-written summary

SM-BGCs have spatially and temporally regulated requirements during infection of wheat heads versus coleoptiles.

Taxon: Fusarium graminearumFusarium graminearumt0
Organ / stage: wheat heads versus coleoptilese0
Interactor: wheatTriticum aestivume0host
Gene: SM-BGCse0
Outcome: spatiotemporal regulation and tissue-dependent requirementse0

Verbatim

e0
“spatiotemporal regulation and tissue-dependent requirements of SM-BGCs during infection of wheat heads versus coleoptiles”
✓ located verbatim in the source · abstract, characters 840–961

t0
“Fusarium graminearum”
✓ located verbatim in the source · title, characters 128–148

Title

A functional atlas of secondary metabolite biosynthetic gene clusters governing growth, stress adaptation, and pathogenicity in Fusarium graminearum

Hao Qi; Liwen Zhao; Luona Xu; et al. Crop Health 2026. doi:10.1007/s44297-026-00070-x

Other claims from this paper (5)

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

BGC36 is critical for full virulence.

Taxon: Fusarium graminearumFusarium graminearumt0
Interactor: wheatTriticum aestivume1
Gene: BGC36e0
Outcome: full virulencee0

Verbatim

e0
“PKS-type BGC36 and NRPS-type BGC47, as critical for full virulence”
✓ located verbatim in the source · abstract, characters 1100–1166

e1
“spatiotemporal regulation and tissue-dependent requirements of SM-BGCs during infection of wheat heads versus coleoptiles”
✓ located verbatim in the source · abstract, characters 840–961

t0
“Fusarium graminearum”
✓ located verbatim in the source · title, characters 128–148

Title

A functional atlas of secondary metabolite biosynthetic gene clusters governing growth, stress adaptation, and pathogenicity in Fusarium graminearum

Hao Qi; Liwen Zhao; Luona Xu; et al. Crop Health 2026. doi:10.1007/s44297-026-00070-x

Other claims from this paper (5)

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

BGC47 is critical for full virulence.

Taxon: Fusarium graminearumFusarium graminearumt0
Gene: BGC47e0
Outcome: full virulencee0

Verbatim

e0
“PKS-type BGC36 and NRPS-type BGC47, as critical for full virulence”
✓ located verbatim in the source · abstract, characters 1100–1166

t0
“Fusarium graminearum”
✓ located verbatim in the source · title, characters 128–148

Title

A functional atlas of secondary metabolite biosynthetic gene clusters governing growth, stress adaptation, and pathogenicity in Fusarium graminearum

Hao Qi; Liwen Zhao; Luona Xu; et al. Crop Health 2026. doi:10.1007/s44297-026-00070-x

Other claims from this paper (5)

Mechanismobservedoriginal resultpositivemeasured

Claim · model-written summary

BGC36 positively regulates deoxynivalenol biosynthesis.

Taxon: Fusarium graminearumFusarium graminearumt0
Gene: BGC36e0
Outcome: deoxynivalenol (DON) biosynthesise0

Verbatim

e0
“BGC36 positively regulates deoxynivalenol (DON) biosynthesis”
✓ located verbatim in the source · abstract, characters 1168–1228

t0
“Fusarium graminearum”
✓ located verbatim in the source · title, characters 128–148

Title

A functional atlas of secondary metabolite biosynthetic gene clusters governing growth, stress adaptation, and pathogenicity in Fusarium graminearum

Hao Qi; Liwen Zhao; Luona Xu; et al. Crop Health 2026. doi:10.1007/s44297-026-00070-x

Other claims from this paper (5)

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

BGC47 disruption compromises cell wall and membrane stress tolerance and is associated with reduced Mgv1 phosphorylation, DON-toxisome formation and DON production.

Taxon: Fusarium graminearumFusarium graminearumt0
Treatment: disruption of BGC47e0
Gene: BGC47e0
Outcome: cell wall/membrane stress tolerancee0
Direction: compromisese0

Not reportedComparator

Verbatim

e0
“disruption of BGC47 compromises cell wall/membrane stress tolerance and is associated with reduced phosphorylation of the kinase Mgv1, impaired DON-toxisome formation, and reduced DON production”
✓ located verbatim in the source · abstract, characters 1238–1432

t0
“Fusarium graminearum”
✓ located verbatim in the source · title, characters 128–148

Title

A functional atlas of secondary metabolite biosynthetic gene clusters governing growth, stress adaptation, and pathogenicity in Fusarium graminearum

Hao Qi; Liwen Zhao; Luona Xu; et al. Crop Health 2026. doi:10.1007/s44297-026-00070-x

Other claims from this paper (5)

Observationobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

TRI5 RNAi mutants had significantly reduced TRI5 expression and NX toxin production in vitro compared with 44211.

Taxon: Fusarium graminearumFusarium graminearumt0
Material: TRI5 RNAi mutantse0
Gene: TRI5e0
Outcome: TRI5 expression and NX toxin productione0
Direction: reducede0
Comparator: 44211e0
Setting: in vitroe0

Verbatim

e0
“Compared with 44211, TRI5 RNAi mutants had significantly reduced TRI5 expression and NX toxin production in vitro”
✓ located verbatim in the source · abstract, characters 695–808

t0
“Fusarium graminearum”
✓ located verbatim in the source · title, characters 26–46

Title

Host-Induced Silencing of Fusarium graminearum TRI5 Reduces Fusarium Head Blight and NX Mycotoxin Contamination in Barley

Guixia Hao; Nicholas Rhoades; Shengming Yang; et al. Molecular Plant-Microbe Interactions 2026. doi:10.1094/mpmi-03-26-0030-r

Other claims from this paper (6)

Intervention effect Barley heads inoculated with TRI5 RNAi mutants and 44211 had similar disease levels.
Intervention effect Barley heads inoculated with TRI5 RNAi mutants had significantly reduced NX toxin compared with 44211-inoculated heads.
Intervention effect TRI5 RNAi barley lines had significantly reduced FHB severity relative to controls.
Intervention effect TRI5 RNAi barley lines had significantly reduced NX-3 relative to controls.
Observation Small RNA sequencing found TRI5-mapping reads in Fusarium RNAi mutants and barley RNAi lines.
Observation TRI5 small RNA mapping patterns were remarkably similar in Fusarium and barley.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 4d had an in vitro EC50 of 1.33 mg/L against Fusarium graminearum.

Taxon: Fusarium graminearumFusarium graminearume1
Outcome: EC 50 valuese0
Value: 1.33e0

Verbatim

e0
“EC 50 values of 0.21, 0.95, 0.64, 1.33, and 0.66 mg L”
✓ located verbatim in the source · abstract, characters 623–676

e1
“against Valsa mali , Botrytis cinerea , Rhizoctonia solani , Fusarium graminearum , and Gaeumannomyces graminis”
✓ located verbatim in the source · abstract, characters 680–791

Title

Discovery of novel 4‐sulfur‐substituted pyrazol‐5‐yl‐benzamide derivatives containing amide/hydrazide/ester moieties as potential succinate dehydrogenase inhibitors

Yantao Li; Yuxin Mu; Jun Xiong; et al. Pest Management Science 2025. doi:10.1002/ps.8943

Other claims from this paper (9)

Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

In vitro, the lipopeptides significantly reduced mycelial radial growth of three F. graminearum sensu stricto strains by up to 84%.

Taxon: F. graminearumFusarium graminearume0
Treatment: CLPse1
Interactor: F. graminearumFusarium graminearume0pathogen
Second interactor: B. velezensis RC218Bacillus velezensise1biocontrol_agent
Outcome: mycelial radial growthe0
Direction: reductione0
Value: up to 84%e0
Setting: In vitroe0

Not reportedComparator

Verbatim

e0
“In vitro experiments showed a significant reduction in the mycelial radial growth (up to 84%) of three F. graminearum sensu stricto strains”
✓ located verbatim in the source · abstract, characters 639–778

e1
“CLPs produced by B. velezensis RC218”
✓ located verbatim in the source · abstract, characters 310–346

Title

Fusarium head blight biocontrol using cyclic lipopeptides produced by Bacillus velezensis RC218

Gustavo Ochoa; Augustina Reynoso; Alicia del Valle Zurita; et al. Biocontrol Science and Technology 2025. doi:10.1080/09583157.2025.2541203

Other claims from this paper (7)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Putrescine globally changed fungal chromatin accessibility.

Taxon: Fusarium graminearumFusarium graminearume1
Treatment: putrescinee1
Outcome: chromatin accessibilitye0

Verbatim

e0
“Putrescine globally alters chromatin accessibility, with the ATP-dependent chromatin remodeler FgIsw1 emerging as a key regulator.”
✓ located verbatim in the source · abstract, characters 505–635

e1
“the phytopathogenic fungus Fusarium graminearum treated with and without putrescine”
✓ located verbatim in the source · abstract, characters 332–415

Title

Fungal chromatin remodeler Isw1 modulates translation via regulating tRNA transcription

Jing Wang; Yueqi Zhang; Jingrui Wang; et al. Nucleic Acids Research 2025. doi:10.1093/nar/gkaf225

Other claims from this paper (7)

Observation FgIsw1 emerged as a key chromatin accessibility regulator.
Intervention effect FgIsw1 deletion did not affect DON biosynthesis gene transcription.
Intervention effect FgIsw1 deletion significantly disrupted tRNA transcription.
Intervention effect FgIsw1 deletion caused a dramatic decline in translation of DON biosynthesis enzymes.
Mechanism FgIsw1 maintains nucleosome phasing in tRNA chromatin regions for efficient tRNA transcription.
Intervention effect The FgIsw1 deletion strain was unable to produce DON.
Intervention effect The FgIsw1 deletion strain lost virulence on the host plant.

Fusarium graminearum 393 claims

393 claims