Claim · model-written summary
Compound 4d gave a protective effect of 93.4% against V. mali infection in apples, versus 68.7% for lead compound A27.
- Taxon
- apples
Malus domesticae0 - Treatment
- compound 4de0
- Interactor
- V. maliCytospora malie0pathogen
- Outcome
- protectivee1
- Direction
- superiore1
- Value
- 93.4%e1
- Qualifier
- 68.7%e1
- Comparator
- lead compound A27e1
Not reportedMaterialGeneCompoundOrgan / stageSecond interactorSecond interactor roleSetting
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“compound 4d effectively prevented V. mali infection in apples”
e1“showing superior protective and curative effects (93.4% and 85.5%) compared to lead compound A27 (68.7% and 57.0%) and commercial fungicide fluxapyroxad (55.4% and 43.6%)”
Title
Yantao Li; Yuxin Mu; Jun Xiong; et al. Pest Management Science 2025. doi:10.1002/ps.8943
Other claims from this paper (9)
- Observation Compound 4d had an in vitro EC50 of 0.21 mg/L against Valsa mali.
- Observation Compound 4d had an in vitro EC50 of 0.95 mg/L against Botrytis cinerea.
- Observation Compound 4d had an in vitro EC50 of 0.64 mg/L against Rhizoctonia solani.
- Observation Compound 4d had an in vitro EC50 of 1.33 mg/L against Fusarium graminearum.
- Observation Compound 4d had an in vitro EC50 of 0.66 mg/L against Gaeumannomyces graminis.
- Intervention effect Compound 4d gave a curative effect of 85.5% against V. mali infection in apples, versus 57.0% for lead compound A27.
- Intervention effect Compound 4d gave a protective effect of 93.4% against V. mali infection in apples, versus 55.4% for fluxapyroxad.
- Intervention effect Compound 4d gave a curative effect of 85.5% against V. mali infection in apples, versus 43.6% for fluxapyroxad.
- Mechanism Enzymatic inhibition assays and molecular docking suggested that compound 4d could serve as a potential SDH inhibitor.