Claim · model-written summary
Overexpression of GoPGF (CGF3) dramatically increased gossypol and related terpenoids in cultured cotton cells.
- Taxon
- Gossypium hirsutum
Gossypium hirsutume3 - Treatment
- Overexpression of Go PGFe2
- Gene
- Go PGFe2
- Outcome
- gossypol and related terpenoidse2
- Direction
- increasee2
- Setting
- cultured cellse2
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e2“Overexpression of Go PGF (synonym CGF 3 ) led to a dramatic increase in gossypol and related terpenoids in cultured cells”
e3“cultivated, tetraploid cotton ( Gossypium hirsutum L.)”
Title
Genes regulating gland development in the cotton plant
Madhusudhana R. Janga; Devendra Pandeya; LeAnne M. Campbell; et al. Plant Biotechnology Journal 2018. doi:10.1111/pbi.13044
Other claims from this paper (9)
- Intervention effect Virus-induced silencing of three gene pairs significantly reduced the number of glands in cotton leaves.
- Intervention effect Silencing of three gene pairs significantly lowered gossypol and related terpenoid levels in cotton.
- Observation The glandless cotton carries a transposon insertion within the coding sequence of the GoPGF (CGF3) gene.
- Intervention effect CRISPR/Cas9 knockout of GoPGF (CGF3) genes produced a glandless cotton phenotype.
- Mechanism The GoPGF (CGF3) gene is concluded to play a critical role in gland formation in cotton.
- Recommendation Seed-specific silencing of CGF genes could eliminate glands and thus gossypol from cottonseed, making it safer as feed.
- Observation Embryos of glanded cotton showed 33 genes expressed exclusively or at higher levels just before gland formation.
- Observation The CGF genes encode transcription factors.
- Observation No sequence differences were found between glanded and glandless cotton for CGF1 and CGF2 gene pairs.