Intervention effectmodel-written summary

GbCAD1 silencing compromised cotton resistance to V. dahliae.

A claim from Proteomic and Virus-induced Gene Silencing (VIGS) Analyses Reveal That Gossypol, Brassinosteroids, and Jasmonic acid Contribute to the Resistance of Cotton to Verticillium dahliae · 2013

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

GbCAD1 silencing compromised cotton resistance to V. dahliae.

Treatment
Silencing of GbCAD1e0
Interactor
V. dahliaeVerticillium dahliaee0pathogen
Gene
GbCAD1e0
Outcome
cotton resistance to V. dahliaee0
Direction
compromisede0

Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Gossypium hirsutum
Gossypium hirsutum · TaxonChriKo · CC BY-SA 3.0 · Wikimedia Commons ↗
Verticillium dahliae
Verticillium dahliae · InteractorHoward F. Schwartz · CC BY 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“Silencing of GbCAD1, a key enzyme involving in gossypol biosynthesis, compromised cotton resistance to V. dahliae”

✓ located verbatim in the source · abstract, characters 1052–1165

Title

Proteomic and Virus-induced Gene Silencing (VIGS) Analyses Reveal That Gossypol, Brassinosteroids, and Jasmonic acid Contribute to the Resistance of Cotton to Verticillium dahliae

Wei Gao; Lu Long; Long-Fu Zhu; et al. Molecular & Cellular Proteomics 2013. doi:10.1074/mcp.m113.031013

Other claims from this paper (10)

Record rev-e348e0021e141d6a3da38b0a268b7e52ca0be558e9fc197bed28857036b5dbbd · schema claims-v0.9 · position 5 in the model’s answer

loss of function · Verticillium dahliae · Gossypium hirsutum (cotton)Positive and negative results

93 papers: 34 positive, 59 negative or no effect

58 papers in the same direction as this claim · 34 in the opposite direction

  1. positive
    GhLac1 suppression conferred cotton resistance to Verticillium dahliae.

    Laccase GhLac1 Modulates Broad-Spectrum Biotic Stress Tolerance via Manipulating Phenylpropanoid Pathway and Jasmonic Acid Synthesis · 2017

    Opposite directionCites this paper

  2. positive
    Simultaneous silencing of three GhWATs increases cotton plant resistance to V. dahliae.

    Cotton WATs Modulate SA Biosynthesis and Local Lignin Deposition Participating in Plant Resistance Against Verticillium dahliae · 2019

    Opposite directionCites this paper

  3. positive
    HDTF1 silencing enhanced cotton resistance to V. dahliae.

    Suppression of the homeobox gene HDTF1 enhances resistance to Verticillium dahliae and Botrytis cinerea in cotton · 2015

    Opposite directionCites this paper

  4. positive
    Silencing HyPRP1 enhanced cotton resistance to V. dahliae.

    HyPRP1 performs a role in negatively regulating cotton resistance to V. dahliae via the thickening of cell walls and ROS accumulation · 2018

    Opposite directionCites this paper

  5. positive
    HIGS in cotton enhanced broad-spectrum resistance to Verticillium wilt.

    Host‐induced gene silencing of a regulator of G protein signalling gene (VdRGS1) confers resistance to Verticillium wilt in cotton · 2018

    Opposite directionCites this paper

  6. positive
    Silencing of GhWIN2 enhanced resistance of cotton to Verticillium dahliae.

    The cotton GhWIN2 gene activates the cuticle biosynthesis pathway and influences the salicylic and jasmonic acid biosynthesis pathways · 2019

    Opposite directionCites this paper

  7. positive
    Host induced silencing of VdChs5 and VdChs7 increased cotton resistance to wilt.

    Chitin synthases containing myosin motor-like domain are required for cell wall integrity and virulence of vascular wilt pathogen Verticillium dahliae · 2023

    Opposite directionCites this paper

  8. positive
    GhERF91 positively regulates the cotton response to Verticillium dahliae, shown by virus-induced gene silencing.

    Cotton ethylene response factor GhERF91 is involved in the defense against Verticillium dahliae · 2023

    Opposite directionCites this paper

84 papers more in this group

See all 93 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.

Functional evidence on GbCAD1

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

GbCAD1

Gossypium hirsutum (cotton)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Gossypium hirsutum (cotton).

Disease resistance1 paper

  1. Promotes
    GbCAD1 silencing compromised cotton resistance to V. dahliae.

    Proteomic and Virus-induced Gene Silencing (VIGS) Analyses Reveal That Gossypol, Brassinosteroids, and Jasmonic acid Contribute to the Resistance of Cotton to Verticillium dahliae · 2013

    loss of function → less of the traitThis claim

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.