Claim · model-written summary
The authors infer that inhibitors stabilize SAURs.
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Verbatim
e0“protein synthesis inhibitors act by stabilizing SAURs”
Title
Induction and superinduction of auxin-responsive mRNAs with auxin and protein synthesis inhibitors.
A.R. Franco; M.A. Gee; T.J. Guilfoyle Journal of Biological Chemistry 1990. doi:10.1016/s0021-9258(18)55475-2
Other claims from this paper (9)
- Intervention effect SAUR abundance rises within minutes after auxin application.
- Intervention effect SAURs accumulated without auxin under inhibited protein synthesis.
- Intervention effect Adding 2,4-dichlorophenoxyacetic acid during protein synthesis inhibition superinduced SAURs.
- Intervention effect Protein synthesis inhibitors did not activate SAUR-gene transcription unlike the synthetic auxin.
- Mechanism The authors infer a labile protein participates in rapid SAUR turnover.
- Observation GH3 did not show this stabilization.
- Observation SAURs were primarily expressed in epidermal and cortical cells, with little vascular expression.
- Intervention effect Cycloheximide-induced SAUR increase was transient and peaked at about one hour.
- Observation Complete protein synthesis inhibition was unnecessary for SAUR accumulation.