Claim · model-written summary
Hexane/ethyl acetate fraction of A. klaineanum trunk bark (AKETF1) has the strongest antiplasmodial activity
- Taxon
- Antrocaryon klaineanum
Antrocaryon klaineanumt0 - Material
- AKETF1e1
- Organ / stage
- trunk barke1
- Outcome
- antiplasmodial activitiese1
- Direction
- strongeste1
- Value
- 4.4 μg/mLe1
Not reportedGeneCompoundInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Antrocaryon klaineanum”
e1“The hexane/ethyl acetate (1:1) fraction of A.klaineanum root bark (AKERF1) and the hexane/ethyl acetate (1:1) fraction of A.klaineanum trunk bark (AKETF1) presented the strongest antiplasmodial activities with IC 50 values of 0.4 and 4.4 μg/mL, respectively”
Title
Y. Fouokeng; H.M. Feumo Feusso; J.E. Mbosso Teinkela; et al. South African Journal of Botany 2018. doi:10.1016/j.sajb.2018.10.008
Other claims from this paper (10)
- Observation Hexane/ethyl acetate fraction of A. klaineanum root bark (AKERF1) has the strongest antiplasmodial activity
- Observation Aridanin from Diospyros conocarpa shows moderate trypanocidal effects
- Observation Antrocarine A from Antrocaryon klaineanum shows moderate trypanocidal effects
- Observation Crude extract of D.conocarpa roots (EDCR) shows moderate trypanocidal effects
- Observation AKERF1 and AKETF1 show moderate trypanocidal effects
- Observation Crude extract of A. klaineanum root bark (AKER) inhibits HIV-1 integrase with attractive activity
- Observation AKETF1 extract inhibits HIV-1 integrase with attractive activity
- Observation Eight compounds were isolated from Diospyros conocarpa
- Observation Six compounds were isolated from Antrocaryon klaineanum
- Recommendation Extracts of A. klaineanum and D. conocarpa are a baseline for new antiplasmodial, antitrypanosomal and anti-HIV drug sources