Claim · model-written summary
Mutations in MED16 significantly suppressed SA-induced defense responses.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae0 - Treatment
- Mutations in MED16e1
- Outcome
- SA-induced defense responsese2
- Direction
- significantly suppressede2
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Here, we report that the Arabidopsis thaliana Mediator subunit16 (MED16) is an essential positive regulator of SAR”
e1“Mutations in MED16 reduced NPR1 protein levels”
e2“These mutations also significantly suppressed SA-induced defense responses”
Title
Xudong Zhang; Chenggang Wang; Yanping Zhang; et al. The Plant Cell 2012. doi:10.1105/tpc.112.103317
Other claims from this paper (7)
- Intervention effect Mutations in MED16 completely compromised biological induction of SAR.
- Intervention effect Mutations in MED16 reduced NPR1 protein levels.
- Intervention effect Mutations in MED16 altered the transcriptional changes induced by Pseudomonas syringae pv tomato (Pst) DC3000/avrRpt2.
- Intervention effect Mutations in MED16 rendered plants susceptible to Pst DC3000/avrRpt2 and to Pst DC3000.
- Intervention effect Mutations in MED16 blocked the induction of several jasmonic acid (JA)/ethylene (ET)-responsive genes.
- Intervention effect Mutations in MED16 compromised resistance to the necrotrophic fungal pathogens Botrytis cinerea and Alternaria brassicicola.
- Mechanism MED16 may be a signaling component between the NPR1 signaling node and the general transcription machinery, relaying signals from both the SA and the JA/ET pathways.