Claim · model-written summary
Six coumarins (1-4, 6 and 7) displayed mild antimycobacterial activity against Mycobacterium tuberculosis H37Ra.
- Taxon
- Pterocaulon redolens
Pterocaulon redolenst0 - Interactor
- Mycobacterium tuberculosis
Mycobacterium tuberculosise4other - Compound
- Six coumarins (1-4, 6, and 7)e4
- Outcome
- mild activitye4
Not reportedMaterialGeneOrgan / stageSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Chemical Constituents of Pterocaulon redolens”
e4“Six coumarins (1-4, 6, and 7) and one flavonoid (8) displayed mild activity against Mycobacterium tuberculosis H 37 Ra”
Title
Chemical Constituents of Pterocaulon redolens
Tsutomu Ishikawa; Mayuree Kanlayavattanakul; Nijsiri Ruangrungsi; et al. Heterocycles 2003. doi:10.3987/com-03-s16
Other claims from this paper (5)
- Observation Coumarin 2',3'-dihydroxypuberulin was isolated for the first time as a natural product from Pterocaulon redolens.
- Observation Ten components, seven coumarins and three flavonoids, were isolated from the aerial parts of Pterocaulon redolens.
- Method / resource Full 1H- and 13C-NMR spectral assignments were reported for the isolated products, including a revision of a previous literature assignment.
- Observation Flavonoid luteolin (8) displayed mild antimycobacterial activity against Mycobacterium tuberculosis H37Ra.
- Observation Flavonoid chrysosplenol C (10) showed moderate cytotoxicity against breast cancer and human small cell lung cancer cell lines, reported as a first finding.