Claim · model-written summary
Jacareubin, isogarcinol, and garcinol were isolated.
- Taxon
- Garcinia buchananiiGarcinia buchananiit0
- Outcome
- jacareubin, isogarcinol, and garcinole0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Verbatim
e0“six known compounds, (2″R,3″R)-preussianon, euxanthone, 2-isoprenyl-1,3,5,6-tetrahydroxyxanthone, jacareubin, isogarcinol, and garcinol.”
t0“Garcinia buchananii”
Title
Antioxidative Compounds from Garcinia buchananii Stem Bark
Timo D. Stark; Mathias Salger; Oliver Frank; et al. Journal of Natural Products 2015. doi:10.1021/np5007873
Other claims from this paper (9)
- Observation The stem-bark extract showed strong antioxidant activity in three assays.
- Observation Fractionation yielded three new compounds: isomanniflavanone, 1,5-dimethoxyajacareubin, and garcinisidone-G.
- Observation Preussianon, euxanthone, and 2-isoprenyl-1,3,5,6-tetrahydroxyxanthone were isolated.
- Observation All compounds were reported for the first time in Garcinia buchananii.
- Observation Absolute configurations were determined through NMR, ECD spectroscopy, and polarimetry.
- Observation The natural products showed high in vitro antioxidant power, especially isomanniflavanone.
- Observation Isomanniflavanone had an H2O2 scavenging EC50 of 8.5 μM.
- Observation Isomanniflavanone had H/L-TEAC values of 3.50/4.95 mmol TE/mmol.
- Observation Isomanniflavanone had H/L-ORAC values of 7.54/14.56 mmol TE/mmol.