Claim · model-written summary
RcSE1 overexpression in Saccharomyces cerevisiae reduced squalene accumulation by 45%.
- Taxon
- Rosa chinensis
Rosa chinensist0 - Treatment
- overexpression of RcSE1e0
- Gene
- RcSE1e0
- Outcome
- squalene accumulatione0
- Direction
- reductione0
- Value
- 45%e0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Rosa chinensis”
e0“In Saccharomyces cerevisiae , overexpression of RcSE1 led to a 45% reduction in squalene accumulation, and alongside an increase in the sterol contents.”
Title
Qiuyu Zhao; Bing Hu; Guiyan Chen; et al. Scientia Horticulturae 2026. doi:10.1016/j.scienta.2026.114751
Other claims from this paper (11)
- Intervention effect Podosphaera pannosa infection upregulated LOC112173431 in rose leaves 29.1-fold versus controls.
- Intervention effect Podosphaera pannosa infection upregulated LOC112174075 in rose leaves 46.8-fold versus controls.
- Mechanism Conserved domains were identified as critical for squalene binding and catalytic activity.
- Observation Molecular docking identified VAL67 and TYR78 as residues involved in substrate interaction.
- Observation Heterologously expressed RcSE1 showed enzymatic activity of 15.43 IU/L.
- Intervention effect RcSE1 overexpression in Saccharomyces cerevisiae increased sterol contents.
- Intervention effect RcSE1 overexpression increased maslinic acid content 46.87 times in T2 Arabidopsis plants.
- Intervention effect RcSE1 overexpression increased betulonic acid content 8.12 times in T2 Arabidopsis plants.
- Intervention effect RcSE1 overexpression increased ganoderic acid B content 1.07 times in T2 Arabidopsis plants.
- Intervention effect RcSE1 overexpression increased ursolic acid content 2.86 times in T2 Arabidopsis plants.
- Mechanism The authors infer that RcSE1 directly activates a pathway critical for insect resistance without mildew infection or hormone signals.