Claim · model-written summary
Hydrogen sulfide induced persulfidation at TaATG6c Cys177 and Cys180.
- Taxon
- wheat
Triticum aestivumt0 - Treatment
- H₂Se0
- Gene
- TaATG6ce0
- Outcome
- persulfidatione0
- Qualifier
- Cys177 and Cys180e0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Cys177 and Cys180 of TaATG6c undergo H₂S-induced persulfidation”
t0“wheat”
Title
Hydrogen sulfide promotes wheat immunity against stripe rust through TaATG6c persulfidation
Ying Ma; Fangfang Peng; Ran Zhao; et al. Stress Biology 2026. doi:10.1007/s44154-026-00292-7
Other claims from this paper (13)
- Intervention effect Exogenous hydrogen sulfide enhanced wheat resistance to stripe rust pathogen.
- Observation Proteomics identified TaATG6c as a pathogen-responsive hydrogen sulfide target.
- Method / resource Structural modeling predicted that two site mutations reduced ATG6c binding to ATG14.
- Intervention effect Silencing TaATG6 promoted fungal growth.
- Observation Pst infection induced TaATG6 expression.
- Intervention effect TaATG6 silencing compromised NaHS-mediated resistance.
- Intervention effect Transient TaATG6 overexpression enhanced wheat stripe rust resistance.
- Intervention effect Cys177 and Cys180 mutations attenuated the resistance effect of TaATG6 overexpression.
- Observation TaATG6c persulfidation was pathogen responsive and dynamic.
- Intervention effect The pathogen responsive persulfidation was abolished in the TaATG6 C177A/C180A mutant.
- Intervention effect Hydrogen sulfide treatment and Pst infection stimulated lipidated ATG8 accumulation.
- Intervention effect TaATG6 silencing largely abolished lipidated ATG8 accumulation.
- Mechanism Authors infer hydrogen sulfide promotes autophagy through TaATG6c persulfidation to enhance wheat resistance.