Claim · model-written summary
Z18 inhibited Alternaria brassicae with EC50 32.5 µg/mL and was reported as having higher activity than azoxystrobin.
Verbatim
e0“Z18 also had the inhibitory activity against the Alternaria brassicae, with an EC50 value of 32.5 µg/mL, which was much higher than azoxystrobin (49.3 µg/mL).”
Title
A potential antifungal agent: Insight into the antifungal mechanism against Phomopsis sp
Chunmei Yuan; Tao Zhang; Jiao Tian; et al. Arabian Journal of Chemistry 2023. doi:10.1016/j.arabjc.2023.105480
Other claims from this paper (8)
- Observation Some synthesized compounds exhibited remarkable antifungal activity.
- Intervention effect Z17 had the strongest activity against Phomopsis sp, with EC50 12.3 µg/mL, superior to both controls.
- Intervention effect Z17 provided 62.5% protective activity against Phomopsis sp on kiwifruit at 200 µg/mL.
- Intervention effect Z18 effectively protected cabbage against Alternaria brassicae infestation.
- Mechanism Z17 disrupted Phomopsis sp cell membrane integrity, affecting normal mycelial growth.
- Intervention effect Z17 changed Phomopsis sp mycelial morphology and cell permeability.
- Intervention effect Z17 increased cytoplasm leakage and MDA contents in Phomopsis sp.
- Mechanism Docking suggested that Z17 could bind the SDH active site and potentially inhibit SDH.