Claim · model-written summary
Compound 5ah gives 100% in vivo efficacy against Erysiphe graminis at 10 μg/mL.
Verbatim
e2“5ah exhibited promising in vivo activity against Erysiphe graminis and Puccinia sorghi Schw. with 100% efficacy at 10 μg/mL and 90% efficacy at 2 μg/mL against P. sorghi Schw.”
Title
Weibo Wang; Zhixinyi Li; Wei Gao; et al. Journal of Agricultural and Food Chemistry 2021. doi:10.1021/acs.jafc.1c01651
Other claims from this paper (6)
- Method / resource Compound 5ai has in vitro activity against Rhizoctonia solani with an EC50 of 1.5 μg/mL, superior to diflumetorim.
- Method / resource Compound 3b has an EC50 of 5.2 μg/mL against Gibberella zeae, better than YZK-C22.
- Method / resource Compound 3c has an EC50 of 4.5 μg/mL against Gibberella zeae, better than YZK-C22.
- Method / resource Compound 5ah gives 90% in vivo efficacy against Puccinia sorghi at 2 μg/mL.
- Method / resource Compound 5ai inhibits pyruvate kinase with an IC50 of 38.8 μmol/L, slightly more active than YZK-C22.
- Observation Compound 5ai is well docked into the active site of the target enzyme PK.
