By organism › Fungi › Glomerellaceae › Colletotrichum orbiculare

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Most of the target compounds strongly inhibited Colletotrichum orbiculare.

Taxon: Colletotrichum orbiculareColletotrichum orbicularee0
Treatment: most of the target compoundse0
Outcome: inhibitory effectse0
Qualifier: excellente0

Verbatim

e0
“The results of the antimicrobial bioassay showed that most of the target compounds displayed excellent inhibitory effects against Xanthomonas oryzae, Rhizoctonia solani, and Colletotrichum orbiculare”
✓ located verbatim in the source · abstract, characters 519–718

Title

Novel 5-Sulfonyl-1,3,4-thiadiazole-Substituted Flavonoids as Potential Bactericides and Fungicides: Design, Synthesis, Three-Dimensional Quantitative Structure–Activity Relationship Studies

Peng Dai; Jian Jiao; Yufei Li; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c06367

Other claims from this paper (10)

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Deletion of SRN1 increased C. orbiculare virulence on cucumber.

Taxon: C. orbiculareColletotrichum orbicularee1
Treatment: SRN1 and SRN2 deletion mutantse1
Interactor: Cucumis sativusCucumis sativuse0host
Gene: SRN1e1
Outcome: virulencee1
Direction: increasede1

Not reportedComparator

Verbatim

e0
“cucumber (Cucumis sativus)”
✓ located verbatim in the source · abstract, characters 654–680

e1
“C. orbiculare SRN1 and SRN2 deletion mutants exhibited increased virulence on the host”
✓ located verbatim in the source · abstract, characters 820–906

Title

Guanosine‐specific single‐stranded ribonuclease effectors of a phytopathogenic fungus potentiate host immune responses

Naoyoshi Kumakura; Suthitar Singkaravanit‐Ogawa; Pamela Gan; et al. New Phytologist 2024. doi:10.1111/nph.19582

Other claims from this paper (8)

Intervention effect SRN1 induces cell death when transiently expressed in Nicotiana benthamiana, dependent on signal peptide and catalytic residues.
Intervention effect SRN2 induces cell death when transiently expressed in Nicotiana benthamiana, dependent on signal peptide and catalytic residues.
Observation SRN genes were pervasive across Colletotrichum species.
Intervention effect SRN1 potentiated cucumber pattern-triggered immunity.
Intervention effect SRN2 potentiated cucumber pattern-triggered immunity.
Intervention effect Deletion of SRN2 increased C. orbiculare virulence on cucumber.
Observation SRN1 specifically cleaved single-stranded RNA at guanosine and left a 3′-end phosphate.
Mechanism Catalytic residues are required for SRN1 and SRN2 to potentiate cucumber responses.

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Deletion of SRN2 increased C. orbiculare virulence on cucumber.

Taxon: C. orbiculareColletotrichum orbicularee1
Treatment: SRN1 and SRN2 deletion mutantse1
Interactor: Cucumis sativusCucumis sativuse0host
Gene: SRN2e1
Outcome: virulencee1
Direction: increasede1

Not reportedComparator

Verbatim

e0
“cucumber (Cucumis sativus)”
✓ located verbatim in the source · abstract, characters 654–680

e1
“C. orbiculare SRN1 and SRN2 deletion mutants exhibited increased virulence on the host”
✓ located verbatim in the source · abstract, characters 820–906

Title

Guanosine‐specific single‐stranded ribonuclease effectors of a phytopathogenic fungus potentiate host immune responses

Naoyoshi Kumakura; Suthitar Singkaravanit‐Ogawa; Pamela Gan; et al. New Phytologist 2024. doi:10.1111/nph.19582

Other claims from this paper (8)

Intervention effect SRN1 induces cell death when transiently expressed in Nicotiana benthamiana, dependent on signal peptide and catalytic residues.
Intervention effect SRN2 induces cell death when transiently expressed in Nicotiana benthamiana, dependent on signal peptide and catalytic residues.
Observation SRN genes were pervasive across Colletotrichum species.
Intervention effect SRN1 potentiated cucumber pattern-triggered immunity.
Intervention effect SRN2 potentiated cucumber pattern-triggered immunity.
Intervention effect Deletion of SRN1 increased C. orbiculare virulence on cucumber.
Observation SRN1 specifically cleaved single-stranded RNA at guanosine and left a 3′-end phosphate.
Mechanism Catalytic residues are required for SRN1 and SRN2 to potentiate cucumber responses.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

AB023a inhibited C . orbiculare with reported MICs in the 1–32 μg/mL range.

Taxon: C . orbiculareColletotrichum orbicularee0
Treatment: AB023ae0
Outcome: minimum inhibitory concentrationse0
Value: 1–32 μg/mLe0

Not reportedComparatorDirection

Verbatim

e0
“AB023a and takanawaene C displayed broad-spectrum antifungal activity against Aspergillus oryzae , Botrytis cinerea , Colletotrichum coccodes , C . gloeosporioides , C . orbiculare , Cylindrocarpon destructans , and Fusarium oxysporum f. sp. lycopersici , showing minimum inhibitory concentrations of 1–32 μg/mL”
✓ located verbatim in the source · abstract, characters 634–945

Title

Pentaene macrolides AB023a and takanawaene C produced by Streptomyces xanthocidicus strain S3 for controlling pepper anthracnose

Byeong Jun Jeon; Ji Eun Kang; Jeong Do Kim; et al. Applied Biological Chemistry 2023. doi:10.1186/s13765-023-00813-2

Other claims from this paper (19)

Observation The S3 culture extract exhibited high adenylate kinase activity against plant pathogens.
Observation AT-1 and AT-2 were isolated from the culture extract.
Observation AT-1 and AT-2 were identified as AB023a and takanawaene C pentaene macrolides.
Intervention effect AB023a inhibited Aspergillus oryzae with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited Botrytis cinerea with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited Colletotrichum coccodes with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited C . gloeosporioides with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited Cylindrocarpon destructans with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited Fusarium oxysporum f. sp. lycopersici with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Aspergillus oryzae with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Botrytis cinerea with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Colletotrichum coccodes with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited C . gloeosporioides with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited C . orbiculare with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Cylindrocarpon destructans with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Fusarium oxysporum f. sp. lycopersici with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited pepper anthracnose concentration-dependently without phytotoxicity, with efficacy comparable to chlorothalonil.
Intervention effect Takanawaene C inhibited pepper anthracnose concentration-dependently without phytotoxicity, with efficacy comparable to chlorothalonil.
Recommendation The authors recommend the S3 polyene macrolides as natural fungicides for plant disease control.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Takanawaene C inhibited C . orbiculare with reported MICs in the 1–32 μg/mL range.

Taxon: C . orbiculareColletotrichum orbicularee0
Treatment: takanawaene Ce0
Outcome: minimum inhibitory concentrationse0
Value: 1–32 μg/mLe0

Not reportedComparatorDirection

Verbatim

e0
“AB023a and takanawaene C displayed broad-spectrum antifungal activity against Aspergillus oryzae , Botrytis cinerea , Colletotrichum coccodes , C . gloeosporioides , C . orbiculare , Cylindrocarpon destructans , and Fusarium oxysporum f. sp. lycopersici , showing minimum inhibitory concentrations of 1–32 μg/mL”
✓ located verbatim in the source · abstract, characters 634–945

Title

Pentaene macrolides AB023a and takanawaene C produced by Streptomyces xanthocidicus strain S3 for controlling pepper anthracnose

Byeong Jun Jeon; Ji Eun Kang; Jeong Do Kim; et al. Applied Biological Chemistry 2023. doi:10.1186/s13765-023-00813-2

Other claims from this paper (19)

Observation The S3 culture extract exhibited high adenylate kinase activity against plant pathogens.
Observation AT-1 and AT-2 were isolated from the culture extract.
Observation AT-1 and AT-2 were identified as AB023a and takanawaene C pentaene macrolides.
Intervention effect AB023a inhibited Aspergillus oryzae with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited Botrytis cinerea with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited Colletotrichum coccodes with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited C . gloeosporioides with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited C . orbiculare with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited Cylindrocarpon destructans with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited Fusarium oxysporum f. sp. lycopersici with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Aspergillus oryzae with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Botrytis cinerea with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Colletotrichum coccodes with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited C . gloeosporioides with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Cylindrocarpon destructans with reported MICs in the 1–32 μg/mL range.
Intervention effect Takanawaene C inhibited Fusarium oxysporum f. sp. lycopersici with reported MICs in the 1–32 μg/mL range.
Intervention effect AB023a inhibited pepper anthracnose concentration-dependently without phytotoxicity, with efficacy comparable to chlorothalonil.
Intervention effect Takanawaene C inhibited pepper anthracnose concentration-dependently without phytotoxicity, with efficacy comparable to chlorothalonil.
Recommendation The authors recommend the S3 polyene macrolides as natural fungicides for plant disease control.

Observationobservedoriginal resultnegativemeasured

Claim · model-written summary

Isolates of four Colletotrichum species were insensitive to boscalid, fluxapyroxad and fluopyram on YBA agar medium.

Taxon: C. gloeosporioides, C. acutatum, C. cereale and C. orbiculareColletotrichum orbiculareColletotrichum acutatumColletotrichum cerealeColletotrichum gloeosporioidese1
Treatment: boscalid, fluxapyroxad and fluopyrame1
Outcome: insensitive (naturally resistant)e1
Setting: YBA agar mediume1

Verbatim

e1
“Isolates of C. gloeosporioides, C. acutatum, C. cereale and C. orbiculare were insensitive (naturally resistant) to boscalid, fluxapyroxad and fluopyram on YBA agar medium”
✓ located verbatim in the source · abstract, characters 297–468

Title

Efficacy of SDHI fungicides, including benzovindiflupyr, against Colletotrichum species

Hideo Ishii; Fan Zhen; Mengjun Hu; et al. Pest Management Science 2016. doi:10.1002/ps.4216

Other claims from this paper (8)

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 4u had 82.16% fungicidal activity against C. orbiculare.

Taxon: C. orbiculare (Berk aLMont) ArxColletotrichum orbicularee0
Outcome: fungicidal activitye0
Direction: goode0
Value: 82.16%e0

Verbatim

e0
“this compound also exhibited good fungicidal activity against C. orbiculare (Berk aLMont) Arx (82.16%)”
✓ located verbatim in the source · abstract, characters 1234–1336

Title

Design, Synthesis, Biological Activities, and 3D‐QSAR of New N,N′‐Diacylhydrazines Containing 2‐(2,4‐dichlorophenoxy)propane Moiety

Xing‐Hai Liu; Li Pan; Yi Ma; et al. Chemical Biology & Drug Design 2011. doi:10.1111/j.1747-0285.2011.01205.x

Other claims from this paper (5)

Intervention effect Most derivatives were more herbicidal against dicotyledonous than monocotyledonous weeds.
Intervention effect The compounds inhibited cucumber radicle growth completely.
Method / resource The herbicidal activity model had reported fit and predictive statistics.
Intervention effect Compound 4u had 94.7% herbicidal activity at 1500 g/ha, below 2,4-D.
Observation The derivatives showed favorable fungicidal activity against five named fungi.

Intervention effectobservedoriginal resultmeasured

Claim · model-written summary

cokel1 disruption mutants form appressoria of irregular shape

Taxon: Colletotrichum orbiculareColletotrichum orbicularet0
Treatment: cokel1 disruption mutantse1
Outcome: shapee1
Direction: irregulare1

Not reportedComparator

Verbatim

t0
“Colletotrichum orbiculare”
✓ located verbatim in the source · title, characters 109–134

e0
“We isolated the gene CoKEL1, encoding a novel kelch repeat protein, from Colletotrichum orbiculare”
✓ located verbatim in the source · abstract, characters 119–217

e1
“Appressoria produced by cokel1 disruption mutants showed irregular shape and impairment of turgor generation”
✓ located verbatim in the source · abstract, characters 341–449

Title

A Kelch Repeat Protein, Cokel1p, Associates with Microtubules and Is Involved in Appressorium Development in Colletotrichum orbiculare

Ayumu Sakaguchi; Toshihiko Miyaji; Gento Tsuji; et al. Molecular Plant-Microbe Interactions 2009. doi:10.1094/mpmi-23-1-0103

Other claims from this paper (7)

Intervention effect cokel1 disruption mutants show impaired turgor generation in appressoria
Intervention effect Mutant appressoria rarely penetrated to form infection hyphae in host epidermal cells
Intervention effect cokel1 mutants had reduced pathogenicity on host leaves compared with the wild type
Intervention effect The cokel1 mutant was more sensitive to cell-wall-degrading enzymes
Observation The cokel1 mutant showed altered labeling with the cell wall stain Calcofluor white
Observation Cokel1p localizes to cortical and spindle microtubules in vegetative hyphae
Mechanism Cokel1p is a microtubule-associated protein involved in infection-related morphogenesis and pathogenicity

Intervention effectobservedoriginal resultmeasured

Claim · model-written summary

cokel1 disruption mutants show impaired turgor generation in appressoria

Taxon: Colletotrichum orbiculareColletotrichum orbicularet0
Treatment: cokel1 disruption mutantse1
Outcome: turgor generatione1
Direction: impairmente1

Not reportedComparator

Verbatim

t0
“Colletotrichum orbiculare”
✓ located verbatim in the source · title, characters 109–134

e1
“Appressoria produced by cokel1 disruption mutants showed irregular shape and impairment of turgor generation”
✓ located verbatim in the source · abstract, characters 341–449

Title

A Kelch Repeat Protein, Cokel1p, Associates with Microtubules and Is Involved in Appressorium Development in Colletotrichum orbiculare

Ayumu Sakaguchi; Toshihiko Miyaji; Gento Tsuji; et al. Molecular Plant-Microbe Interactions 2009. doi:10.1094/mpmi-23-1-0103

Other claims from this paper (7)

Intervention effect cokel1 disruption mutants form appressoria of irregular shape
Intervention effect Mutant appressoria rarely penetrated to form infection hyphae in host epidermal cells
Intervention effect cokel1 mutants had reduced pathogenicity on host leaves compared with the wild type
Intervention effect The cokel1 mutant was more sensitive to cell-wall-degrading enzymes
Observation The cokel1 mutant showed altered labeling with the cell wall stain Calcofluor white
Observation Cokel1p localizes to cortical and spindle microtubules in vegetative hyphae
Mechanism Cokel1p is a microtubule-associated protein involved in infection-related morphogenesis and pathogenicity

Intervention effectobservedoriginal resultmeasured

Claim · model-written summary

Mutant appressoria rarely penetrated to form infection hyphae in host epidermal cells

Taxon: Colletotrichum orbiculareColletotrichum orbicularet0
Treatment: mutante2
Outcome: penetrated to form infection hyphaee2
Direction: rarelye2

Not reportedComparator

Verbatim

t0
“Colletotrichum orbiculare”
✓ located verbatim in the source · title, characters 109–134

e2
“the mutant appressoria rarely penetrated to form infection hyphae in host epidermal cells”
✓ located verbatim in the source · abstract, characters 454–543

Title

A Kelch Repeat Protein, Cokel1p, Associates with Microtubules and Is Involved in Appressorium Development in Colletotrichum orbiculare

Ayumu Sakaguchi; Toshihiko Miyaji; Gento Tsuji; et al. Molecular Plant-Microbe Interactions 2009. doi:10.1094/mpmi-23-1-0103

Other claims from this paper (7)

Intervention effect cokel1 disruption mutants form appressoria of irregular shape
Intervention effect cokel1 disruption mutants show impaired turgor generation in appressoria
Intervention effect cokel1 mutants had reduced pathogenicity on host leaves compared with the wild type
Intervention effect The cokel1 mutant was more sensitive to cell-wall-degrading enzymes
Observation The cokel1 mutant showed altered labeling with the cell wall stain Calcofluor white
Observation Cokel1p localizes to cortical and spindle microtubules in vegetative hyphae
Mechanism Cokel1p is a microtubule-associated protein involved in infection-related morphogenesis and pathogenicity

Colletotrichum orbiculare 15 claims

15 claims