Abstract
Iron mobilization responses are induced by low iron supply at transcriptional level. In tomato, the basic helix-loop-helix gene FER is required for induction of iron mobilization. Using molecular-genetic techniques, we analyzed the function of BHLH029, named FRU (FER-like regulator of iron uptake), the Arabidopsis thaliana homolog of the tomato FER gene. The FRU gene was mainly expressed in roots in a cell-specific pattern and induced by iron deficiency. FRU mutant plants were chlorotic, and the FRU gene was found necessary for induction of the essential iron mobilization genes FRO2 (ferric chelate reductase gene) and IRT1 (iron-regulated transporter gene). Overexpression of FRU resulted in an increase of iron mobilization responses at low iron supply. Thus, the FRU gene is a mediator in induction of iron mobilization responses in Arabidopsis, indicating that regulation of iron uptake is conserved in dicot species.
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Claims 5
Claim · model-written summary
The FRU gene is expressed mainly in roots of Arabidopsis thaliana in a cell-specific pattern.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae4 - Organ / stage
- rootse1
- Gene
- FRUe1
- Outcome
- expressede1
- Qualifier
- in a cell-specific patterne1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e4“the Arabidopsis thaliana homolog of the tomato FER gene”
e1“The FRU gene was mainly expressed in roots in a cell-specific pattern and induced by iron deficiency”
Claim · model-written summary
Iron deficiency induces the FRU gene in Arabidopsis thaliana.
- Taxon
- Arabidopsis thalianaArabidopsis thalianae4
- Treatment
- iron deficiencye1
- Gene
- FRUe1
- Outcome
- FRU genee1
- Direction
- inducede1
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e4“the Arabidopsis thaliana homolog of the tomato FER gene”
e1“The FRU gene was mainly expressed in roots in a cell-specific pattern and induced by iron deficiency”
Claim · model-written summary
FRU mutant plants of Arabidopsis thaliana were chlorotic.
- Taxon
- Arabidopsis thalianaArabidopsis thalianae4
- Material
- FRU mutante2
- Outcome
- chlorotice2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e4“the Arabidopsis thaliana homolog of the tomato FER gene”
e2“FRU mutant plants were chlorotic, and the FRU gene was found necessary for induction of the essential iron mobilization genes FRO2 (ferric chelate reductase gene) and IRT1 (iron-regulated transporter gene)”
Claim · model-written summary
The FRU gene is necessary for induction of the FRO2 and IRT1 iron mobilization genes.
- Taxon
- Arabidopsis thalianaArabidopsis thalianae4
- Treatment
- FRU mutante2
- Gene
- FRO2 (ferric chelate reductase gene) and IRT1e2
- Outcome
- induction of the essential iron mobilization genese2
- Direction
- increaseinferrede2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e4“the Arabidopsis thaliana homolog of the tomato FER gene”
e2“FRU mutant plants were chlorotic, and the FRU gene was found necessary for induction of the essential iron mobilization genes FRO2 (ferric chelate reductase gene) and IRT1 (iron-regulated transporter gene)”
Claim · model-written summary
Overexpression of FRU increased iron mobilization responses at low iron supply.
- Taxon
- Arabidopsis thalianaArabidopsis thalianae4
- Treatment
- Overexpression of FRUe3
- Gene
- FRUe3
- Outcome
- iron mobilization responsese3
- Direction
- increasee3
- Qualifier
- at low iron supplye3
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e4“the Arabidopsis thaliana homolog of the tomato FER gene”
e3“Overexpression of FRU resulted in an increase of iron mobilization responses at low iron supply”
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