Abstract
Early detection of salt stress is vital for plant survival and growth. Still, the molecular processes controlling early salt stress perception and signaling are not fully understood. Here, we identified salt-responsive ERF1 (SERF1), a rice (Oryza sativa) transcription factor (TF) gene that shows a root-specific induction upon salt and hydrogen peroxide (H2O2) treatment. Loss of SERF1 impairs the salt-inducible expression of genes encoding members of a mitogen-activated protein kinase (MAPK) cascade and salt tolerance-mediating TFs. Furthermore, we show that SERF1-dependent genes are H2O2 responsive and demonstrate that SERF1 binds to the promoters of MAPK kinase kinase6 (MAP3K6), MAPK5, dehydration-responsive element bindinG2A (DREB2A), and zinc finger protein179 (ZFP179) in vitro and in vivo. SERF1 also directly induces its own gene expression. In addition, SERF1 is a phosphorylation target of MAPK5, resulting in enhanced transcriptional activity of SERF1 toward its direct target genes. In agreement, plants deficient for SERF1 are more sensitive to salt stress compared with the wild type, while constitutive overexpression of SERF1 improves salinity tolerance. We propose that SERF1 amplifies the reactive oxygen species-activated MAPK cascade signal during the initial phase of salt stress and translates the salt-induced signal into an appropriate expressional response resulting in salt tolerance.
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Claims 9
Claim · model-written summary
Rice SERF1 shows root-specific induction upon salt and H2O2 treatment.
- Taxon
- Rice
Oryza sativat0 - Organ / stage
- roote0
- Treatment
- salt and hydrogen peroxide (H2O2) treatmente0
- Outcome
- inductione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e0“shows a root-specific induction upon salt and hydrogen peroxide (H2O2) treatment”
Claim · model-written summary
Loss of SERF1 impairs salt-inducible expression of MAPK cascade genes and salt tolerance-mediating transcription factor genes in rice.
- Taxon
- RiceOryza sativat0
- Treatment
- Loss of SERF1e1
- Outcome
- salt-inducible expression of genese1
- Direction
- impairse1
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e1“Loss of SERF1 impairs the salt-inducible expression of genes encoding members of a mitogen-activated protein kinase (MAPK) cascade and salt tolerance-mediating TFs”
Claim · model-written summary
SERF1-dependent genes are H2O2 responsive in rice.
- Taxon
- RiceOryza sativat0
- Outcome
- SERF1-dependent genese2
- Qualifier
- H2O2 responsivee2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e2“we show that SERF1-dependent genes are H2O2 responsive”
Claim · model-written summary
SERF1 binds to the promoters of MAP3K6, MAPK5, DREB2A and ZFP179 in vitro and in vivo.
- Taxon
- RiceOryza sativat0
- Gene
- MAP3K6e4
- Outcome
- binds to the promoterse4
- Qualifier
- in vitro and in vivoe4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e4“SERF1 binds to the promoters of MAPK kinase kinase6 (MAP3K6), MAPK5, dehydration-responsive element bindinG2A (DREB2A), and zinc finger protein179 (ZFP179) in vitro and in vivo”
Claim · model-written summary
SERF1 directly induces its own gene expression in rice.
- Taxon
- RiceOryza sativat0
- Gene
- SERF1e3
- Outcome
- gene expressione3
- Qualifier
- directly inducese3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e3“SERF1 also directly induces its own gene expression”
Claim · model-written summary
MAPK5 phosphorylation of SERF1 enhances SERF1 transcriptional activity toward its direct target genes.
- Taxon
- RiceOryza sativat0
- Gene
- MAPK5e5
- Outcome
- enhanced transcriptional activity of SERF1e5
- Qualifier
- a phosphorylation target of MAPK5e5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e5“SERF1 is a phosphorylation target of MAPK5, resulting in enhanced transcriptional activity of SERF1 toward its direct target genes”
Claim · model-written summary
Rice plants deficient for SERF1 are more sensitive to salt stress than wild type.
- Taxon
- RiceOryza sativat0
- Material
- deficient for SERF1e6
- Treatment
- salt stresse6
- Outcome
- sensitive to salt stresse6
- Direction
- moree6
- Comparator
- wild typee6
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e6“plants deficient for SERF1 are more sensitive to salt stress compared with the wild type, while constitutive overexpression of SERF1 improves salinity tolerance”
Claim · model-written summary
Constitutive overexpression of SERF1 improves rice salinity tolerance.
- Taxon
- RiceOryza sativat0
- Treatment
- constitutive overexpression of SERF1e6
- Outcome
- salinity tolerancee6
- Direction
- improvese6
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e6“plants deficient for SERF1 are more sensitive to salt stress compared with the wild type, while constitutive overexpression of SERF1 improves salinity tolerance”
Claim · model-written summary
SERF1 is proposed to amplify the reactive oxygen species-activated MAPK cascade signal during the initial phase of salt stress.
- Taxon
- RiceOryza sativat0
- Gene
- SERF1e7
- Outcome
- reactive oxygen species-activated MAPK cascade signale7
- Qualifier
- during the initial phase of salt stresse7
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Initial Response to Salt Stress in Rice”
e7“SERF1 amplifies the reactive oxygen species-activated MAPK cascade signal during the initial phase of salt stress”
The same questions in other papers
salinity · molecular: expression · Oryza sativa (rice)Positive and negative results
22 papers in the same direction as this paper · 49 in the opposite direction
- positive
- negative
- positive
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